Results 201 to 210 of about 60,584 (224)

BCR-ABL

2006
openaire   +1 more source

Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia

Nature Reviews Cancer, 2007
Sandra W Cowan-Jacob, Andreas Hochhaus
exaly  

BCR-ABL Inhibitor

2020
openaire   +1 more source

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

New England Journal of Medicine, 2001
Brian J Druker, Moshe Talpaz, Hagop M Kantarjian   +2 more
exaly  

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells

Nature Medicine, 1996
Brian J Druker
exaly  

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl

Cancer Cell, 2005
Ellen L Weisberg, Paul W Manley, Sandra W Cowan-Jacob   +2 more
exaly  

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

Cell, 1991
Ann Marie Pendergast, Alexander J Muller, Owen N Witte   +2 more
exaly  

The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

Cancer Cell, 2005
Paolo Neviani, Rossana Trotta, Bradley W Blaser   +2 more
exaly  

Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

New England Journal of Medicine, 2001
Brian J Druker, Charles L Sawyers, Hagop M Kantarjian   +2 more
exaly  

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance

Cancer Cell, 2009
Christopher A Eide, Victor M Rivera, Jeffrey W Tyner   +2 more
exaly