eLife, 2016 Exercise induces beneficial responses in the brain, which is accompanied by an increase in BDNF, a trophic factor associated with cognitive improvement and the alleviation of depression and anxiety. However, the exact mechanisms whereby physical exercise
Sama F Sleiman +11 more
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The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function [PDF]
Cell, 2003 Michael Egan +11 more
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Effect of aerobic training on heat shock protein 27 and brain-derived neurotrophic factor in hippocampus and prefrontal cortex of type II diabetic rats [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2021 Background: According to the experimental studies, the levels of heat shock protein 27 (HSP27) and brain-derived neurotrophic factor (BDNF) are decreased in diabetes which is associated with impaired cognitive function in the brain.
Saeed Dabagh Nikukheslat +2 more
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Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
Nature Neuroscience, 2023 Psychedelics produce fast and persistent antidepressant effects and induce neuroplasticity resembling the effects of clinically approved antidepressants.
R. Moliner +32 more
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Amelioration of amyloid beta (Aβ1-40) neurotoxicity by administration of silibinin; a behavioral and biochemical assessment [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Alzheimer’s disease (AD), the most common cause of dementia, is one of the leading causes of morbidity and death in the world. Currently, treatment mostly used to slow down the disease progression.
Tahereh Alihosseini +4 more
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Effect of treadmill exercise on catalepsy and the expression of the BDNF gene in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine male NMRI mice [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): It is known that treadmill exercise has beneficial effects on the nervous system. The brain-derived neurotrophic factor (BDNF) plays a role in such effects.
Neda Nikokalam Nazif +4 more
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International Journal of Molecular Sciences, 2022 Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal survival and growth. The signaling cascades initiated by BDNF and its receptor are the key regulators of synaptic plasticity, which plays important role in ...
Khairunnuur Fairuz Azman, R. Zakaria
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The Role of BDNF Val66met Polymorphism on the Learning of a Motor Sequence Task: The Challenge of Visual-Spatial and Motor Coordination Systems [PDF]
رشد و یادگیری حرکتی ورزشی, 2022 Introduction: Brain-derived neurotrophic factor (BDNF) is a protein that is highly expressed in the structures of the central nervous system and affects synaptic plasticity and the acquisition of motor and cognitive skills.
Abolfazl Shayan +3 more
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Protective effect of Allium atroviolaceum-synthesized SeNPs on aluminum-induced brain damage in mice
Open Chemistry, 2022 This study evaluated the possible neuroprotective effect of Allium atroviolaceum extract (AaE)-synthesized selenium nanoparticles (SeNPs) on aluminum (Al)-induced neurotoxicity in mice, explaining the likely mechanisms. Mice were divided into five groups:
Othman Mohamed S. +11 more
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International Journal of Molecular Sciences, 2020 Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin receptor kinase B (TrkB) and the low affinity p75 neurotrophin receptor (p75NTR ...
L. Colucci-D'Amato +2 more
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