Results 121 to 130 of about 122,805 (310)

Effects of acute and chronic high-intensity interval training on serum irisin, BDNF and apelin levels in male soccer referees [PDF]

Journal of Men's Health
This study was aimed to investigate the effects of acute and chronic High Intensity Interval Training (HIIT) on Irisin, BDNF (brain-derived neurotrophic factor), and Apelin levels. The study included twenty-one male soccer referees.
Hamza Kucuk, Mehmet Soyler, Tulay Ceylan, Levent Ceylan, Fatma Nese Sahin   +4 more
doaj   +1 more source

Global Trends and Advances in Traumatic Brain Injury

Brain Health, EarlyView.
ABSTRACT Traumatic brain injury (TBI) remains a major global public health challenge, contributing substantially to morbidity and mortality while imposing a significant socioeconomic burden. In recent years, notable progress has been made in understanding TBI pathophysiology, classification, monitoring, and treatment.
Yuan Zhuang, Xixian Liao, Jiyao Jiang, Guoyi Gao   +3 more
wiley   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

LOCAL SUPPLEMENTATION OF BRAINDERIVED NEUROTROPHIC FACTOR FOR THE TREATMENT OF NEURONAL DAMAGE.

, 2010
The importance of nerve growth factors, especially brain-derived neurotrophic factor (BDNF) in the regulation of neuronal survival and plastic changes in morphology and function has been increasingly studied during the recent years.
Su, Tao
core  

Long-term gene therapy causes transgene-specific changes in the morphology of regenerating retinal ganglion cells

, 2012
Recombinant adeno-associated viral (rAAV) vectors can be used to introduce neurotrophic genes into injured CNS neurons, promoting survival and axonal regeneration.
Rodger Jennifer, Hellström Mats, Alan R Harvey, Jennifer Rodger, Mats Hellström, Hellström, M., Robertson, D., Harvey, A.R., Donald Robertson, Drummond Eleanor S., Harvey Alan R., Eleanor S Drummond, Rodger, J., Drummond, E.S., Robertson Donald   +14 more
core   +1 more source

Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays

Cytoskeleton, EarlyView.
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz, Benjamin Powers, Jayne Aiken   +2 more
wiley   +1 more source

BDNF and TNF-alpha polymorphisms in memory

, 2013
Here, we investigate the genetic basis of human memory in healthy individuals and the potential role of two polymorphisms, previously implicated in memory function.
Lea, R. A., Haupt, L. M., McKenzie, K., Maher, B. H., Sutherland, H. G., Yogeetha, B. S., Okolicsyani, R. K., Griffiths, L. R., Griffiths, LR (reprint author), Griffith Univ, Genom Res Ctr, Griffith Hlth Inst, Gold Coast, Qld 4222, Australia., Chan, R. C. K., Shum, D. H. K.   +10 more
core  

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Serum BDNF and P300 Latency: Potential Markers of Mild Cognitive Impairment in Depressed Patients [Letter]

Neuropsychiatric Disease and Treatment
Mengwei Jiang Department of Anesthesiology, Zhejiang Provincial People’s Hospital, Hangzhou, Zhejiang, 310014, People’s Republic of ChinaCorrespondence: Mengwei Jiang, Department of Anesthesiology, Zhejiang Provincial People’s Hospital,
Jiang M
doaj  

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, EarlyView.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source