Results 131 to 140 of about 122,805 (310)

Down-regulation of serotonergic genes expression in the raphe nuclei of midbrain under chronic social defeat stress in male mice

, 2011
Background: There is ample experimental evidence supporting the hypothesis that the brain serotonergic system is involved in the control of chronic social defeat stress (CSDS), depression and anxiety.
Ul’yana A. Boyarskikh, Natalya P. Bondar, Natalia N. Kudryavtseva, Maxim L. Filipenko   +3 more
core  

BDNF

, 2016
Alignment of the nuclear locus ...
Alberto R. Puente-Rolon (3315414), Puente-Rolon, Alberto R., Stesha A. Pasachnik (3315420), Collar, David C., David C. Collar (3251418), Robert G. Reynolds (3315417), Reynolds, Robert G., Revell, Liam J., Pasachnik, Stesha A., Matthew L. Niemiller (414619), Liam J. Revell (412818), Niemiller, Matthew L.   +11 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Consumption of Ginkgo biloba Extract and Swimming Training on NMDA and BDNF Plasma in Untrained Girls

Journal of Medicinal Plants, 2015
Background: Ginko biloba stimulate blood circulation to the brain. As a result of insufficiency to improve blood flow to the brain. Objective: The aim of this study was to investigate the effect of eight weeks endurance training swimming on BDNF and NMDA
B Hajirezaii, A Barari, A Abbassi Daloii
doaj  

The supporting role of physical exercise in the prevention end treatment of neurodegenerative and mental diseases

Baltic Journal of Health and Physical Activity
The aim of the article is to draw attention to the possibility of using physical exercises in treating neurodegenerative diseases such as Parkinson’s, Alzheimer’s, multiple sclerosis, dementia as well as mental disorders, particularly depression.
Celestyna GRZYWNIAK
doaj   +1 more source

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

Epilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

BDNF [PDF]

Current Biology, 2002
openaire   +2 more sources

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Blood BDNF concentrations reflect brain-tissue BDNF levels across species

, 2010
Brain-derived neurotrophic factor (BDNF) is involved in synaptic plasticity, neuronal differentiation and survival of neurons. Observations of decreased serum BDNF levels in patients with neuropsychiatric disorders have highlighted the potential of BDNF ...
Anders B. Klein, Martin A. Santini, Christoffer Clemmensen, Gitte M. Knudsen, Maribel Rios, Ettrup, Anders, Rios, Maribel, Anders Ettrup, Klein, Anders B, Williamson, Rebecca, Clemmensen, Christoffer, Susana Aznar, Knudsen, Gitte M, Aznar, Susana, Santini, Martin A, Rebecca Williamson   +15 more
core   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source