Results 191 to 200 of about 196,397 (352)

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Prognostic impact of endocrine therapy and BDNF-TrkB axis in breast cancer brain metastases. [PDF]

J Neurooncol
Kim J, Shin K, Lee A, Lee J.
europepmc   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Serum BDNF helps identify favorable subgroups in HCC patients treated with PD-L1 inhibitors and anti-angiogenic TKIs. [PDF]

Ther Adv Med Oncol
Gong C, Huang J, Cao D, Liu T, Cai Q, You S, Sun Y, Jiang Z, Wang W, Yang L, Zhao H, Zhang W, Zhou A.   +12 more
europepmc   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Effect of Valproate on Serum BDNF and MMP-9 in Pediatric Epilepsy. [PDF]

J Epilepsy Res
Borisagar A, Gupta R, Narang M, Halder S, Mehndiratta M.   +4 more
europepmc   +1 more source

Regulation of BDNF-TrkB Signaling and Potential Therapeutic Strategies for Parkinson’s Disease [PDF]

, 2020
Wook Jin
openalex   +1 more source

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu, Wen‐Juan Wang, Ting‐Ting Zhang, Qi‐Chong Yang, Haliminai Dilimulati, Song‐Tao An   +5 more
wiley   +1 more source

Transcranial Stimulation Methods in the Treatment of MDD Patients-The Role of the Neurotrophin System. [PDF]

Int J Mol Sci
Selakovic D, Mitrovic M, Ljujic B, Janjic V, Milovanovic D, Jovicic N, Simovic Markovic B, Corovic I, Vasiljevic M, Milanovic P, Stevanovic M, Rosic S, Randjelovic S, Fetahovic E, Chopra A, Milosavljevic J, Rosic G.   +16 more
europepmc   +1 more source

Locating BDNF [PDF]

Nature Reviews Neuroscience, 2012
openaire   +1 more source