Results 191 to 200 of about 93,782 (262)

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Journal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads, Megan H. Hagenauer, Jinglin Xiong, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Elizabeth Flandreau, Stanley Watson Jr., Huda Akil   +8 more
wiley   +1 more source

Fingolimod Effects on Motor Function and BDNF-TrkB Signaling in a Huntington's Mouse Model Are Disease-Stage-Dependent. [PDF]

Int J Mol Sci
Nguyen KQ, Rymar VV, Sadikot AF.
europepmc   +1 more source

Sleep‐Related Attentional Bias in Insomnia: A Drift Diffusion Model Approach

Journal of Sleep Research, EarlyView.
ABSTRACT Cognitive models propose that insomnia is maintained in part by selective attention to sleep‐related information, yet reaction‐time indices alone offer limited mechanistic specificity. We investigated sleep‐related attentional bias in adolescents and young adults with insomnia disorder (n = 201; aged 15–24 years; DSM‐5) using a sleep‐related ...
Isla Tsz Kwan Hui, Tommy Ho‐Fung Chung, Sing‐Hang Cheung, Nazanin Biabani, Panagis Drakatos, Romola S. Bucks, Sharon L. Naismith, David O'Regan, Veena Kumari, Dieter Riemann, Toby Wise, Shirley Xin Li, Ivana Rosenzweig   +12 more
wiley   +1 more source

Optogenetic stimulation attenuates central post-stroke pain via BDNF/TrkB signaling pathway modulation in the ascending pain modulation system. [PDF]

Sci Rep
Gu YJ, Chang J, Deng F, Deng C.
europepmc   +1 more source

Rs12516 A allele elevates the risk of colorectal cancer via functional CeRNA network of BDNF-AS, miR-4704-5p and BRCA1. [PDF]

BMC Cancer
Liu D, Fan Z, Zhang T, Li X, Ming C, Wu J, Lu X, Sun D.   +7 more
europepmc   +1 more source

Amygdala-hippocampus circuit regulates stress coping via mGluR5-dependent BDNF signaling. [PDF]

Mol Cells
Kim TE, Choi TY, Koo JW, Kim J.
europepmc   +1 more source

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

Obesity Reviews, EarlyView.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source

Dairy intake in relation to metabolic health status, serum levels of brain-derived neurotrophic factor and adropin: a cross-sectional study on Iranian adults. [PDF]

BMJ Open
Moradmand Z, Amani Tirani S, Shahdadian F, Hajhashemy Z, Rouhani P, Saneei P.   +5 more
europepmc   +1 more source