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BDNF and Cerebellar Ataxia

Current Drug Research Reviews
Abstract: Brain-derived neurotrophic factor (BDNF) has been proposed as a treatment for neurodegeneration, including diseases of the cerebellum, where BDNF levels or those of its main receptor, TrkB, are often diminished relative to controls, thereby serving as replacement therapy.
Robert Lalonde   +2 more
openaire   +2 more sources

Sodium Chloride Enhances the Storage and Conformational Stability of BDNF and PEG-BDNF

Pharmaceutical Research, 2001
BDNF, a noncovalent homodimer, was modified by covalently attaching polyethylene glycol (PEG) with an average molecular weight of 20kDa to the N-terminal methionine. Stability of modified BDNF (PEG-BDNF) in aqueous solution was compared to BDNF after storage at elevated temperature in the presence and absence of NaCl.SDS-PAGE. Light Scattering and Size
W J, Callahan   +3 more
openaire   +2 more sources

The BDNF Val66Met polymorphism and smoking

Neuroscience Letters, 2008
Although the brain derived neurotrophic factor (BDNF) has been mainly investigated in the context of depression and anxiety disorders, several studies also suggest an association between BDNF and smoking. BDNF represents a protein which crucially influences several processes in the cell ranging from growth to apoptosis. A functional variant of the BDNF
Christian, Montag   +4 more
openaire   +2 more sources

Research Progress on BDNF and Depression

ACS Chemical Neuroscience
Depression is a potentially life-threatening psychiatric disorder that affects the physical and mental health of millions of individuals worldwide. It can manifest at any stage of life, inducing profound emotional despondency, negative cognitions, and, in severe cases, suicidal ideation, often accompanied by physical symptoms, bringing a significant ...
Yahong Qiu   +3 more
openaire   +2 more sources

???????????????? ???????????????????????????????? ???????????? BDNF ???????????? ?? ?????????????????? ?? ?????????????????????????????? ???????????????????? ???????????? ?????????????????????? ??????????????????????????: ?????????????????? ???????????????? ?????? ?????????????????????? ?? ???????????? ?????????????????????????? ??????????????

2017
Blood plasma brain???derived neurotrophic factor (BDNF) levels were investigated in elderly and old patients with subcortical vascular mild cognitive disorders (SVMCD). Reduction of plasma BDNF levels correlated with some parameters of executive dysfunction, reflecting disorders of the link between the prefrontal cortex and subcortical structures due ...
openaire   +1 more source

BDNF

2001
Katherine A. Fitzgerald   +3 more
openaire   +1 more source

BDNF

2012
Keith Hill   +12 more
openaire   +1 more source

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