Results 51 to 60 of about 133,818 (257)

The effect of 6 weeks Tai chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2017
The aim of this study was to determine the effect of Tai Chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke.
منیژه نوروزیان   +2 more
doaj   +1 more source

Association of the G>A (rs6265) polymorphism in the brain derived neurotrophic factor gene (BDNF) with post-training derived neurotrophic factor gene (BDNF) with post-training changes in Caucasian women changes in Caucasian women

open access: yesBaltic Journal of Health and Physical Activity, 2023
The brain-derived neurotrophic factor (BDNF) rs6265 (G196A; Val66Met) polymorphism has been associated with obesity and type 2 diabetes, with contradictory results involving either A or G as the risk allele.
Katarzyna Switala   +5 more
doaj   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

open access: yesAdvanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick   +4 more
wiley   +1 more source

The Effect of three month aerobic exercise whit moderate intensity on BDNF, and cognitive performance in 50-65 years old women with syndrome metabolic [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2017
Aim: The aim of this research was investigation the effect of twelve week aerobic exercise whit moderate intensity on on BDNF, and cognitive performance in 50-65 years old women with syndrome metabolic.Methods: 24 women with metabolic syndrome (MetS ...
علی اوصالی   +4 more
doaj   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

open access: yesAdvanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn   +17 more
wiley   +1 more source

BDNF-AS targets the binding sequence of BDNF mRNA.

open access: yes, 2016
(A) Luciferase reporter vectors were constructed. (B) In BV-2 cells, the cells were co-transfected with aluciferase reporter vector and Renilla vector and then transduced with lentiviral vectors.
Lifang Xu (1339929)   +4 more
core   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

The mimetic of the brain neurotrophic factor GSB-106 has neuroprotective and neuroregenerative effects in experimental ischemic stroke

open access: yesФармакокинетика и Фармакодинамика, 2022
Background. A dimeric dipeptide mimetic of the brain-derived neurotrophic factor loop 4, bis(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide (GSB-106), which activates TrkB, PI3K/AKT, MAPK/ERK and PLC-γ1 was created at the V. V.
P. Yu. Povarnina   +3 more
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

open access: yesAdvanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait   +7 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Home - About - Disclaimer - Privacy