Results 51 to 60 of about 184,218 (302)

Effects of environmental enrichment upon ethanol-induced conditioned place preference and pre-frontal BDNF levels in adolescent and adult mice [PDF]

, 2017
Environmental enrichment (EE) provides a non-pharmacological tool to alter drug-induced reward, yet its effects on ethanol-induced reward remain controversial. We analyzed adolescent vs.
Camarini, Rosana, Hoffmann, Lucas Barbosa, Marianno, Priscila, Pautassi, Ricardo Marcos, Rae, Mariana, Rueda, André Veloso, Suarez, Andrea Beatriz   +6 more
core   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

The Effect of three month aerobic exercise whit moderate intensity on BDNF, and cognitive performance in 50-65 years old women with syndrome metabolic [PDF]

فیزیولوژی ورزش و فعالیت بدنی, 2017
Aim: The aim of this research was investigation the effect of twelve week aerobic exercise whit moderate intensity on on BDNF, and cognitive performance in 50-65 years old women with syndrome metabolic.Methods: 24 women with metabolic syndrome (MetS ...
علی اوصالی, سیروس چوبینه, رحمان سوری, علی اصغر رواسی, حسین مصطفوی   +4 more
doaj   +1 more source

A network map of BDNF/TRKB and BDNF/p75NTR signaling system [PDF]

Journal of Cell Communication and Signaling, 2013
Neurotrophic factors are growth factors, which play an essential role in the development and maintenance of nervous system. These include members of the nerve growth factor (NGF) family, known as neurotrophins. Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), neurotrophin 4 (NT4/5) and neurotrophin 6 (NT-6 ...
Varot K, Sandhya, Rajesh, Raju, Renu, Verma, Jayshree, Advani, Rakesh, Sharma, Aneesha, Radhakrishnan, Vishalakshi, Nanjappa, Jayasuryan, Narayana, B L, Somani, Kanchan K, Mukherjee, Akhilesh, Pandey, Rita, Christopher, T S Keshava, Prasad   +12 more
openaire   +2 more sources

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Relationship between BDNF and oxytocin

Comprehensive Psychoneuroendocrinology, 2023
Converging, albeit scattered data mainly gathered in animals indicate that the neurotrophin brain-derived neurotrophic factor (BDNF) and the nonapeptide oxytocin (OT) interact in a cooperative way. Data in humans are really limited and indirect. Therefore, the aim of the present study was to explore the possible existence of a link between OT and BDNF ...
Marazziti D., Baroni S., Mucci F., Palego L., Arone A., Betti L., Palermo S., Giannaccini G., Carbone M. G., Dell'Osso L.   +9 more
openaire   +4 more sources

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

The mimetic of the brain neurotrophic factor GSB-106 has neuroprotective and neuroregenerative effects in experimental ischemic stroke

Фармакокинетика и Фармакодинамика, 2022
Background. A dimeric dipeptide mimetic of the brain-derived neurotrophic factor loop 4, bis(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide (GSB-106), which activates TrkB, PI3K/AKT, MAPK/ERK and PLC-γ1 was created at the V. V.
P. Yu. Povarnina, T. A. Antipova, I. O. Logvinov, D. M. Nikiforov   +3 more
doaj   +1 more source

Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex [PDF]

, 2006
Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because sensitivity to inflammation is not equal in all brain structures, a direct relationship is not clear.
Argüelles Castilla, Sandro, Ayala Gómez, Antonio, Fernández Villarán, Ruth, Herrera Carmona, Antonio José, Martínez de Pablos, Rocío, Venero Recio, José Luis   +5 more
core   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

Advanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang, Yundong Li, Xin Wang, Yaning Hou, Wei Deng, Meng Zheng, Yan Zou, Bingyang Shi   +7 more
wiley   +1 more source