From ball-milling to bead-milling technology: rapid optimization and scale-up of a one-pot Wittig olefination–Diels–Alder reaction sequence using an agitator bead mill [PDF]
RSC MechanochemistryMechanochemical methods offer a sustainable alternative to traditional solution-based synthesis, yet their scalability beyond laboratory-scale ball mills remains a challenge and often requires lengthy re-optimization for larger scales.
Nina Biedermann +4 more
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Comparison of DNA extraction methods for detecting African swine fever virus in feed and environmental samples [PDF]
Frontiers in Veterinary ScienceAfrican swine fever (ASF) is a fatal viral disease of domestic and wild pigs, with mortality rates reaching up to 100%. In the absence of a safe and effective vaccine in non-endemic countries, it is imperative for the swine industry to implement enhanced
Taeyong Kwon +6 more
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Comparison of ultrasound contrast agent production by sonication and mechanical agitation [PDF]
Ultrasonics SonochemistryMicrobubbles (MBs) are surfactant-coated gas vesicles used widely in ultrasound imaging and increasingly for therapy. MBs can be produced by a range of methods, most commonly involving sonication and/or agitation.
Jovana Katrinka-Mavrak +4 more
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RNAlater-compatible protocol for nuclei isolation from radical prostatectomy prostate cancer resections, enabling single-nucleus resolution RNA-seq [PDF]
Scientific ReportsWe present an optimised protocol for single-nucleus isolation from RNAlater-preserved prostate cancer (PC) resections that enables transcriptomically robust snRNA-seq.
Magdalena Julita Krystkiewicz-Orzechowska +8 more
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Classification of Particles Dispersed by Bead Milling with Electrophoresis
KONA Powder and Particle Journal, 2014 The purpose of the present study is to develop a new particle classification technique and apparatus to replace centrifugal separation method, where continuous operation for classification is impossible because of ...
Tetsuya Yamamoto +4 more
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Study on the Effects of Grinding Factor and Scaling up in Grinding Using Horizontal Dry Bead Mill [PDF]
MATEC Web of Conferences, 2021 Effect of grinding factor and scaling up were carried out by grinding using horizontal dry bead mill. For the experiments, 2 sizes of horizontal dry bead mills with different capacities, lab and manufacturing scale, were used to study scaling up and down.
Tamura Takahiro, Kimata Mitsumasa
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Equation model of disintegration and agglomeration to analyze the bead mill performance
Nihon Kikai Gakkai ronbunshu, 2023 The equation model of disintegration and agglomeration has been developed to analyze the performance of the bead mill. The equation model, derived under the assumption that the frequency of disintegration depends on the volume ratio of the agglomerates ...
Masayuki TANAKA +3 more
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Pharmaceutics, 2022 Activated carbon (AC) could be potentially useful as a drug carrier in fiber polymer scaffolds destined for prolonged drug delivery. To be introduced, AC must be ground into smaller-sized particles to be introduced in scaffolds, as most biocompatible ...
Zhanna K. Nazarkina +7 more
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Crystals, 2021 The synthesis of Mg-Al layered double hydroxide (LDH) was explored, through a one-step wet mechanochemical route, with the use of a NETZSCH LME 1 horizontal bead mill.
Brenda Antoinette Barnard +1 more
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Minoxidil Nanoparticles Targeting Hair Follicles Enhance Hair Growth in C57BL/6 Mice
Pharmaceutics, 2022 We previously found that 1% minoxidil (MXD) nanoparticles prepared using a bead mill method led to an increase I n hair follicle delivery and hair growth in C57BL/6 mice. In the present study, we designed a nanoparticle formulation containing 5% MXD (MXD-
Yoshihiro Oaku +7 more
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