Nanocrystal Preparation of Poorly Water-Soluble Drugs with Low Metal Contamination Using Optimized Bead-Milling Technology [PDF]
Pharmaceutics, 2022 Nanocrystal preparation using bead milling is an important technology to enhance the solubility of poorly water-soluble drugs. However, there are safety concerns regarding the metal contaminants generated during bead milling.
Hironori Tanaka
exaly +4 more sources
High Effective Preparation of Amorphous-Like Si Nanoparticles Using Spark Erosion Followed by Bead Milling [PDF]
Nanomaterials, 2021 This work aims to prepare the silicon nanoparticles with the nanocrystal-embedded amorphous structure through spark erosion followed by bead milling. Spark erosion breaks up monocrystal silicon ingots into micro/nanoparticles, refines the crystal grains,
Mingcai Zhao
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Development of a Semi-Mechanistic Modeling Framework for Wet Bead Milling of Pharmaceutical Nanosuspensions [PDF]
PharmaceuticsThis study aimed to develop a practical semi-mechanistic modeling framework to predict particle size evolution during wet bead milling of pharmaceutical nanosuspensions over a wide range of process conditions and milling scales.
Helen Yao, Ecevit Bilgili, Gulenay Guner
exaly +4 more sources
Evaluation of two different semi-automated homogenization techniques in microbiological diagnosis of periprosthetic joint infection: disperser vs. bead milling method [PDF]
BMC Infectious Diseases, 2022 Background In microbiological diagnosis of periprosthetic joint infection (PJI) there is no consensus regarding the most suitable and optimal number of specimens to be cultured or the most effective technique of tissue processing.
Heime Rieber +10 more
doaj +2 more sources
From ball-milling to bead-milling technology: rapid optimization and scale-up of a one-pot Wittig olefination–Diels–Alder reaction sequence using an agitator bead mill [PDF]
RSC MechanochemistryMechanochemical methods offer a sustainable alternative to traditional solution-based synthesis, yet their scalability beyond laboratory-scale ball mills remains a challenge and often requires lengthy re-optimization for larger scales.
Nina Biedermann +4 more
doaj +2 more sources
Artificial intelligence versus statistical modeling and optimization of continuous bead milling process for bacterial cell lysis [PDF]
Frontiers in Microbiology, 2016 For a commercially viable recombinant intracellular protein production process, efficient cell lysis and protein release is a major bottleneck. The recovery of recombinant protein, cholesterol oxidase (COD) was studied in a continuous bead milling ...
Shafiul Haque +14 more
doaj +2 more sources
Do Mixtures of Beads with Different Sizes Improve Wet Stirred Media Milling of Drug Suspensions?
Pharmaceutics, 2023 The impacts of bead sizes and bead mixtures on breakage kinetics, the number of milling cycles applied to prevent overheating, and power consumption during the nanomilling of drug (griseofulvin) suspensions were investigated from both an experimental and
Helen Yao, Ecevit Bilgili, Gulenay Guner
exaly +3 more sources
A Ni(OH)2/Ti3+–titania photocatalyst produced via wet fine-bead milling and accelerated hydrogen production from seawater [PDF]
RSC AdvancesNi(OH)2/Ti3+-doped titania prepared by wet fine-bead milling exhibited a hydrogen production rate 45 times higher than that of pristine titania under UV and visible light in the presence of a sacrificial agent.
Shoichi Somekawa +4 more
doaj +2 more sources
Classification of Particles Dispersed by Bead Milling with Electrophoresis
KONA Powder and Particle Journal, 2014 The purpose of the present study is to develop a new particle classification technique and apparatus to replace centrifugal separation method, where continuous operation for classification is impossible because of ...
Tetsuya Yamamoto +4 more
doaj +3 more sources
Bioresource Technology, 2017 The disintegration of three industry relevant algae (Chlorella vulgaris, Neochloris oleoabundans and Tetraselmis suecica) was studied in a lab scale bead mill at different bead sizes (0.3-1mm). Cell disintegration, proteins and carbohydrates released into the water phase followed a first order kinetics.
MHM, Carl Safi, Maria J Barbosa
exaly +6 more sources