Results 61 to 70 of about 1,309,062 (296)

TRIBOTECHNICAL CHARACTERISTICS OF CARBON-BEARING LUBRICANTS [PDF]

Proccedings of International Scientific Conference "BALTTRIB 2017", 2017
The development of technology for manufacturing nanostructured substances in amounts that could suffice an interlaboratory research is a high priority task for the implementation of nanoproducts. The ultra dispersiblis clusters of synthetic carbon are used as on extra component in polymeric materials.
А. Voznyakovskii, Y. Auchynnikau, V. Liopo, Y. Eisymont   +3 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Shear Strength and Ultimate Bearing Capacity of Silt-Based Foamed Concrete Under Local Vertical Loading

Buildings
With the rapid development of lightweight and environmentally friendly building materials, foamed concrete has been widely adopted as a novel material for lightweight filling and foundation applications.
Chuanyi Ma, Jun Wang, Ning Zhang, Chuyi Wang, Shengtao Zhang, Yuchen Tao, Shurong Lou, Qingshuo Sun, Xianfu Ren, Hongbo Zhang   +9 more
doaj   +1 more source

Combined Effect of Rarefaction and Effective Viscosity on Micro-Elasto-Aerodynamic Lubrication Performance of Gas Microbearings

Micromachines, 2019
Elastic deformation and gaseous rarefaction effects are of great importance to the static and dynamic characteristics of gas microbearings. Based on the effective viscosity model of Veijola, the governing equations can be solved by the partial derivative
Yao Wu, Lihua Yang, Tengfei Xu, Haoliang Xu   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Experimental Study on the Vertical Bearing Characteristic Model of Pile Groups in Complex Interactive Karst Pile Foundations

Buildings
In order to study the bearing characteristics of pile groups under the coupling of multiple caves, the influence of the interaction between the crossing cave, the underlying inclined cave, the pile-side cave, and the underlying cave on the ultimate ...
Xinquan Wang, Yongle Tian, Haibo Hu, Chen Liu, Haitao Chen, Jun Hong   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Comparison and Optimization of Bearing Capacity of Three Kinds of Photovoltaic Support Piles in Desert Sand and Gravel Areas

Buildings
In recent years, the advancement of photovoltaic power generation technology has led to a surge in the construction of photovoltaic power stations in desert gravel areas.
Xiaojun Su, Zhanhai Li, Qi Wang, Jinxiao Li, Xinyu Xie, Xiang Mao, Zhifeng Ren, Jiankun Liu   +7 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source