Results 81 to 90 of about 1,309,062 (296)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Experimental Study on Bearing Characteristics of Pile-Anchor Foundations for Floating Offshore Wind Turbines Under Inclined Loading

Journal of Marine Science and Engineering
Pile-anchor foundations, serving as one of the anchoring solutions to ensure the safety and stability of floating offshore wind turbines, are primarily subjected to inclined loading induced by anchor chain forces, resulting in significantly different ...
Yuxuan Wang, Pingyu Liu, Bo Liu, Jiaqing Shu, Huiyuan Deng, Mingxing Zhu, Xiaojuan Li, Jie Chen, Haoran Ouyang   +8 more
doaj   +1 more source

Assessment of the operating characteristics of the SSME LOX turbopump pump-end bearing [PDF]

A bearing/shaft model of the SSME LOX turbopump was developed using the SHABERTH bearing/shaft math modeling computer code. A previously developed bearing/shaft thermal model of the SSME LOX turbopump turbine and bearing was used in conjunction with ...
New, L. S., Tiller, B. K.
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Eccentric Taylor-Couette Flow with orbital motion of the inner cylinder [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011), Christl, A, Egbers, C, Herzog, N   +3 more
core  

Rotary mechanical circulatory support systems

, 2017
A detailed survey of the current trends and recent advances in rotary mechanical circulatory support systems is presented in this paper. Rather than clinical reports, the focus is on technological aspects of these rehabilitating devices as a reference ...
Bonnell, Mark, Elahinia, Mohammad, Gupta, Rajesh, Hosseinipour, Milad   +3 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Comparative Experimental Study on Bearing Capacity of Roof Beneath Single Piles and Pile Groups in Karst Area

Buildings
By designing and conducting indoor model tests on single piles and 2 × 2 pile groups under four working conditions—underlying cave, overlying cave, pile penetrating underlying cave, and beaded caves—the failure mode of the roof was explored, and its ...
Xinquan Wang, Haitao Chen, Haibo Hu, Chen Liu, Yongle Tian, Jun Hong   +5 more
doaj   +1 more source

Analysis on Load-bearing Characteristics under Different Oil Film Thicknesses of Hydrostatic Bearing Based on Dynamic Mesh Method

Journal of Harbin University of Science and Technology, 2017
Ｒesearch on the bearing characteristics of heavy hydrostatic bearing in heavy equipment manufacturing industry，considering the influence of film thickness on the bearing capacity and pressure distribution of hydrostatic bearing under different working ...
ZHANG Yan-qin, KONG Xiang-bin, GUO Li-li, CHENG Hai-kuo, LI Ｒui   +4 more
doaj   +1 more source

Simulation of non-linear bearing forces for post-stability investigation [PDF]

Different types of bearing designs were developed to improve dynamic properties of rotor-bearing systems. Elliptical bearings, multisleeve bearings, tilting pad and other designs such as herringbone groove were utilized to increase resistance to the ...
Krodiewski, J. M., Krynicki, K., Parszewski, Z. A., Salek, A. E.   +3 more
core   +1 more source