Results 71 to 80 of about 250,541 (308)
Effect of ascorbic acid on reduced glutathione level in arsenic-loaded isolated liver tissues of rat
Bangladesh Journal of Pharmacology, 2006 Isolated liver tissues of rat were loaded with trivalent arsenic and were exposed in presence and absence of ascorbic acid. The amount of reduced glutathione (GSH) in normal liver tissue was 52.0 0.2 g/g protein.
Beauty Saha
doaj +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
A Two-Sided Ontological Solution to the Sleeping Beauty Problem [PDF]
, 2010 I describe in this paper an ontological solution to the Sleeping Beauty problem. I begin with describing the hyper-entanglement urn experiment. I restate first the Sleeping Beauty problem from a wider perspective than the usual opposition between halfers
Paul, Franceschi
core
Complex Systems, 2015 Complex systems and their underlying convoluted networks are ubiquitous, all we need is an eye for them. They pose problems of organized complexity which cannot be approached with a reductionist method. Complexity science and its emergent sister network science both come to grips with the inherent complexity of complex systems with an holistic strategy.
openaire +4 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 1960 Several contestants from the International Beauty Congress line up with official at airport following arrival for pageant.
core +4 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The measure of existence of a quantum world and the Sleeping Beauty Problem [PDF]
, 2013 An attempt to resolve the controversy regarding the solution of the Sleeping Beauty Problem in the framework of the Many-Worlds Interpretation led to a new controversy regarding the Quantum Sleeping Beauty Problem.
Vaidman, Lev +2 more
core
Pilot Study: Thread Rhinoplasty With Different Methods of Barbed Thread Implantation
Plastic and Reconstructive Surgery, Global OpenBackground:. Thread rhinoplasty is a minimally invasive procedure with short downtime and high patient satisfaction. Although it is known that the effectiveness of rhinoplasty varies depending on the method of thread placement, there have been no studies
Takahiko Tamura, MD, PhD +6 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source