Results 71 to 80 of about 62,296 (265)

Evaluation of the Efficacy of a 2-MNG-Containing Serum on Improving Skin Tone and Hyperpigmentation

open access: yesDermatology and Therapy
Introduction Hyperpigmentation disorders and skin tone unevenness are a very frequent concern worldwide, especially in China; 2-mercaptonicotinoyl glycine (2-MNG, Melasyl®) is an innovative anti-pigmentation ingredient which binds with melanin precursors,
Rui Li   +15 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Digital transformation in public procurement: opportunities and challenges in South African municipalities

open access: yesJournal of Social Sciences
This study explores the opportunities and challenges associated with digital transformation in public procurement within South African municipalities.
ZINDI, Beauty
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Predictors of Dissatisfaction After Polydioxanone Thread Lift: A Multicenter Retrospective Analysis

open access: yesPlastic and Reconstructive Surgery, Global Open
Background:. Polydioxanone (PDO) thread lift is a widely used technique for minimally invasive facial rejuvenation. Although the technical outcomes and complications are well-documented, postoperative dissatisfaction remains underexplored, particularly ...
Kohki Okumura, MD   +3 more
doaj   +1 more source

Making beauty necessary and necessity beautiful

open access: yesEuropean Journal for Research on the Education and Learning of Adults, 2019
The article shows how unemployed working-class women in South Africa, through collective aesthetic experiences, achieved a sense of catharsis that strengthened the resolve to work towards creating alternatives. The text is based on a series of popular education workshops that were recorded in sound and images, and interviews with individual emerging ...
openaire   +3 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Multicenter Review of More Than 110,000 Facial Thread Lifting Cases From a Cosmetic Surgery Group

open access: yesPlastic and Reconstructive Surgery, Global Open
Background:. Thread lifting is a minimally invasive aesthetic procedure that has gained popularity for facial rejuvenation. However, large-scale multicenter studies assessing trends, patient characteristics, and procedural variations are limited.
Takahiko Tamura, MD, PhD   +3 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

In Vitro and Ex Vivo Investigations on the Tolerance and Safety of a 3 kDa Sodium Hyaluronate for Topical Application

open access: yesCosmetics
(1) Background: Low-molecular-weight hyaluronic acid displays moisturizing and anti-aging properties and reduces UV-induced inflammation when applied topically.
Morgane De Tollenaere   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy