Results 61 to 70 of about 11,761 (260)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Exploring Societal Fears of Aging and Loss of Beauty in Disney Film “Tangled” and Indian Film “Yashoda”: A Feminist Film Analysis

open access: yesГалактика медиа: журнал медиа исследований
The fear of aging and the loss of beauty is a pervasive societal issue that transcends cultural boundaries, often manifesting in the media and film industry. This paper examines the 2010 animated film “Tangled” and an Indian Film “Yashoda” (2022) through
Bhuvaneswari Gopalakrishnan   +2 more
doaj   +1 more source

Beauty in the Standard Model and Beyond [PDF]

open access: yesAIP Conference Proceedings, 2006
7 pages, 5 postscript figures, contributed to the Proceedings of CIPANP 2006: 9th Conference on the Intersections of Particle and Nuclear Physics, Westin Rio Mar Beach, Puerto Rico, 30 May - 3 Jun ...
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Beauty Salons are Key Potential Sources of Disease Spread

open access: yesInfection and Drug Resistance, 2021
Najwa Menwer Alharbi, Hanan Mohammed Alhashim King Abdelaziz University, Science College, Biology Department, Jeddah, Saudi ArabiaCorrespondence: Najwa Menwer AlharbiKing Abdelaziz University, Science College, Biology Department, P.O. Box: 80200, Jeddah,
Alharbi NM, Alhashim HM
doaj  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Female body perception: social norms, criticism, and the impact of weight perception

open access: yesInternational Journal of Qualitative Studies on Health & Well-Being
Purpose This study aims to explore the multifaceted nature of women's body perception and the personal and social factors that influence it. The research investigates how societal expectations, health concerns, and self-perception intersect in shaping ...
Reşat Sadık, Gizem Nur Yılmaz
doaj   +1 more source

Reconceptualizing “Ugliness”:

open access: yesCrossings
The socio-cultural construction of beauty simultaneously generates a normative understanding of unattractiveness as well, since these properties exist in binary within popular perceptions.
Ahmed Abdullah Bin Farooqi Rayhan
doaj   +1 more source

Occidentalisation of Beauty Standards: Eurocentrism in Asia

open access: yes, 2020
Beauty standards have long been set in place within society. However the origins of such beauty standards are a topic of discussion and frequently up for debate. Our paper takes a look into the origins, impacts, and implications of beauty standards within various regions of Asia, including Central Asian, South Asia, East Asia, and the Middle East and ...
Chen, Toby   +4 more
openaire   +1 more source

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