Results 101 to 110 of about 193,785 (353)

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

An improved negative selection algorithm based on the hybridization of cuckoo search and differential evolution for anomaly detection [PDF]

open access: yes, 2018
The biological immune system (BIS) is characterized by networks of cells, tissues, and organs communicating and working in synchronization. It also has the ability to learn, recognize, and remember, thus providing the solid foundation for the ...
Ayodele Nojeem, Lasisi
core  

Conflicting Loyalties: Cognitive Abstraction Drives Whistleblowing Behavior Among Those Who Value Loyalty

open access: yesSocial Justice Research
Abstract Potential whistleblowers, that is, people contemplating revealing potentially damaging information about unethical or unlawful behavior to a third party, are often described as facing a conflict between loyalty and fairness. Yet, whistleblowers often may feel a sense of conflicting loyalties: loyalty towards the party (e.g., a ...
Gijs van Houwelingen   +2 more
openaire   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

The Mediating Role of Behavioral Brand Loyalty in the Effect of Consumer Innovation Barriers on Online Smartphone Purchase Intention

open access: yesUluslararası Ekonomi, İşletme ve Politika Dergisi
This study aims to determine the mediating role of behavioral brand loyalty in the effect of consumer innovation barriers on online smartphone purchase intention.
Nilgün Tuzcu
doaj   +1 more source

New-Age Branding and the Public Sector [PDF]

open access: yes, 2010
{Excerpt} Branding is a means to identify a company’s products or services, differentiate them from those of others, and create and maintain an image that encourages confidence among clients, audiences, and partners. Until the mid-1990s, brand management—
Serrat, Olivier
core   +1 more source

The accommodation experiencescape: a comparative assessment of hotels and Airbnb [PDF]

open access: yes, 2017
PURPOSE: Accommodations providers in the sharing economy are increasingly competing with the hotel industry vis-à-vis the guest experience. Additionally, experience-related research remains underrepresented in the hospitality and tourism literature ...
Lehto, Xinran   +2 more
core   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

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