Results 161 to 170 of about 1,231,135 (287)

Protease‐Activated Theranostic Nanomedicine for Endometriosis Treatment

open access: yesAdvanced Functional Materials, EarlyView.
Endometriosis is a chronic gynecological disorder that affects a substantial proportion of reproductive‐aged women. In this study, we identify aberrant overexpression of matrix metalloproteinase‐9 (MMP‐9) in endometriotic lesions and develop a novel multifunctional nanomedicine that integrates MMP‐9‐targeted therapy, ratiometric photoacoustic (PA ...
Panangattukara Prabhakaran Praveen Kumar   +9 more
wiley   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

open access: yesAdvanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li   +10 more
wiley   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Multifunctional Photochromic Piezoionic Eutectogels Through Interfacial Nanoparticle Engineering

open access: yesAdvanced Functional Materials, EarlyView.
Photochromic WO3 nanoparticles enable photoresponsive piezoionics in deep eutectic solvent‐based eutectogels by coupling photoinduced electronic processes with pressure‐driven ionic transport. Interfacial nanoparticle engineering enhances ionic mobility and electromechanical output, while reversible photoactivation modulates the electrical response ...
Saúl Carrasco‐Saavedra   +9 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

Measuring Blood Plasma Glutamine Levels Using a Nanopore‐Based Sensor

open access: yesAdvanced Healthcare Materials, EarlyView.
Glutamine (GLN) is a biomarker useful for predicting toxic ammonia accumulation. Here, we used a biosensor based on the Cytolysin A (ClyA) nanopore coupled with the GLN‐specific protein substrate‐binding domain 2 (SBD2) to demonstrate real‐time measurement of GLN in blood plasma, highlighting the potential for future point‐of‐care applications ...
Sofia B. Relvas   +9 more
wiley   +1 more source

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