Results 201 to 210 of about 42,152 (307)

Noncanonical beige fat thermogenesis [PDF]

Nature Reviews Endocrinology, 2017
openaire   +1 more source

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

First-principles investigation of transition-metal doped Al₂B₂ and AlB₄ monolayers for spintronics. [PDF]

RSC Adv
Wang J, Luo X.
europepmc   +1 more source

eLife Assessment: Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

Michael Czech
openalex   +1 more source

Angiogenic factor regulates beiging [PDF]

Nature Reviews Endocrinology, 2016
openaire   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, Volume 13, Issue 12, 27 February 2026.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Eating behavior patterns in relation to obesity phenotypes and beige adipose tissue content with a focus on young women; a narrative review. [PDF]

Front Nutr
Walkiewicz KW, Dzięgielewska-Gęsiak S, Myrcik D, Bednarczyk M, Muc-Wierzgoń M.   +4 more
europepmc   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Tracking DNA damage localization and chromatin remodeling in live cells using time-resolved quantitative analysis of DNA counterstains. [PDF]

Cell Mol Life Sci
Paternò G, Longo E, Lanzanò L.
europepmc   +1 more source

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

Advanced Science, Volume 13, Issue 8, 9 February 2026.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang, Huanyu Wang, Qianqian Kang, Ruping Pan, Rui He, Min Yang, Jiadai Liu, Xuemin Peng, Yuyu Xie, Hongyan Deng, Wenshe Wang, Zengzhe Zhu, Jing Ge, Yulian Liu, Ronghui Gao, Yaming Guo, Peng Yu, Limeng Pan, Danpei Li, Pema Maretich, Xiaoping Luo, Xuefeng Yu, Yong Chen   +22 more
wiley   +1 more source