Results 91 to 100 of about 7,234 (170)

Induction of Beige-Like Adipocytes in 3T3-L1 Cells

Journal of Veterinary Medical Science, 2014
There are two types of brown adipocytes: classical brown adipocytes that form the brown fat depots and beige adipocytes that emerge in the white fat depots. Beige adipocytes have a low level of uncoupling protein 1 (Ucp1) expression in the basal state, but Ucp1 expression is increased in response to β adrenergic receptor activation.
ASANO, Hiroki, KANAMORI, Yohei, HIGURASHI, Satoshi, NARA, Takayuki, KATO, Ken, MATSUI, Tohru, FUNABA, Masayuki   +6 more
openaire   +3 more sources

Exploring Adipose Tissue Complexity Through Omics Approaches: Implications for Health and Disease

Cells
Adipose tissues (ATs) are dynamic and heterogeneous organs divided into three distinct categories, including white, beige, and brown ATs. Collectively, they contribute to systemic energy homeostasis in various ways.
Rajaa Sebaa
doaj   +1 more source

Rewiring Adipocyte Plasticity: The Redox–Mitochondrial Axis as a Driver of Beige Fat Immunometabolism and Adipose Inflammation

Biomolecules
Obesity is a major health crisis that impacts social and economic burdens worldwide, and it is being studied intensively to understand the molecular mechanisms and regulators of this complex condition.
Faycal Aissa-Brahim, Shuwen Yang, Xunyong Zhou, Zhong Li, Su Bu   +4 more
doaj   +1 more source

Counter-regulation Of Bifunctional Adipocyte Regulators Promotes Adipocyte Beiging

PURPOSE: Obesity, a global epidemic affecting over 890 million individuals, is characterized by excessive white adipose tissue (WAT) accumulation and impaired energy expenditure. Beiging of WAT, via the induction of thermogenic brown-like adipocytes, presents a transformative approach to reverse metabolic dysfunction.
Charbel Saad, Nikhil Hajirnis, Seray Er, Meilene Hanaki, Sashank Reddy   +4 more
openaire   +4 more sources

Decoding temporal thermogenesis: coregulator selectivity and transcriptional control in brown and beige adipocytes

Adipocyte
In mammals, brown adipose tissue (BAT) and beige adipocytes in white adipose tissue (WAT) play pivotal roles in maintaining body temperature and energy metabolism.
Yong Geun Jeon, Sun Won Kim, Jae Bum Kim
doaj   +1 more source

Lactate Conversion by Lactate Dehydrogenase B Is Involved in Beige Adipocyte Differentiation and Thermogenesis in Mice. [PDF]

Nutrients, 2023
Guo B, Shu H, Luo L, Liu X, Ma Y, Zhang J, Liu Z, Zhang Y, Fu L, Song T, Qiao Y, Zhang C.   +11 more
europepmc   +1 more source

Rutin Maintains the Thermogenic Phenotype of Beige Adipocytes and Concomitantly Suppresses Mitophagy Against Obesity in HFD Mice

Metabolites
Background: The browning of white adipose tissue for thermogenesis is an effective strategy for combating obesity. The formation of beige adipocytes is reversible, making their maintenance a key therapeutic target.
Jianmei Li, Kexin Li, Shengnan Li, Jingxun Cui, Shuangying Zhou, Huiwen Wu   +5 more
doaj   +1 more source

Mitochondrial RNA stimulates beige adipocyte development in young mice. [PDF]

Nat Metab, 2022
Hoang AC, Sasi-Szabó L, Pál T, Szabó T, Diedrich V, Herwig A, Landgraf K, Körner A, Röszer T.   +8 more
europepmc   +1 more source

Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT. [PDF]

Mol Metab, 2023
Choi KM, Ko CY, An SM, Cho SH, Rowland DJ, Kim JH, Fasoli A, Chaudhari AJ, Bers DM, Yoon JC.   +9 more
europepmc   +1 more source

Human RSPO1 Mutation Represses Beige Adipocyte Thermogenesis and Contributes to Diet-Induced Adiposity. [PDF]

Adv Sci (Weinh), 2023
Sun Y, Zhang J, Hong J, Zhang Z, Lu P, Gao A, Ni M, Zhang Z, Yang H, Shen J, Lu J, Xue W, Lv Q, Bi Y, Zeng YA, Gu W, Ning G, Wang W, Liu R, Wang J.   +19 more
europepmc   +1 more source