Metabolic programming of a beige adipocyte phenotype by genistein. [PDF]
Mol Nutr Food Res, 2017 Scope Promoting the development of brown or beige adipose tissue may protect against obesity and related metabolic features, and potentially underlies protective effects of genistein in mice.
Aziz SA +5 more
europepmc +8 more sources
A Method to Induce Brown/Beige Adipocyte Differentiation from Murine Preadipocytes [PDF]
Bio-Protocol, 2021 Adipocytes exhibit different morphological and functional characteristics, depending on their anatomical location, developmental origin, and stimulus. While white adipocytes tend to accumulate energy as triglycerides, brown and beige adipocytes tend to ...
Andréa Rocha +3 more
doaj +3 more sources
Identification of an alternative ligand‐binding pocket in peroxisome proliferator‐activated receptor gamma and its correlated selective agonist for promoting beige adipocyte differentiation [PDF]
MedCommThe pharmacological activation of peroxisome proliferator‐activated receptor gamma (PPARγ) is a convenient and promising strategy for promoting beige adipocyte biogenesis to combat obesity‐related metabolic disorders.
Qiang Tian +8 more
doaj +4 more sources
In vitro analyses of paracrine effects of murine classically activated macrophage on beige adipocyte metabolism [PDF]
STAR Protocols, 2022 Summary: The communication between macrophage and adipocyte plays a critical role in the initiation and development of metabolic inflammation, which is difficult to study in vivo.
Jingfei Yao, Dongmei Wu, Yifu Qiu
doaj +2 more sources
The Beige Adipocyte as a Therapy for Metabolic Diseases. [PDF]
Int J Mol Sci, 2019 Adipose tissue is traditionally categorized into white and brown relating to their function and morphology. The classical white adipose tissue builds up energy in the form of triglycerides and is useful for preventing fatigue during periods of low caloric intake and the brown adipose tissue more energetically active, with a greater number of ...
Lizcano F.
europepmc +7 more sources
Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte [PDF]
Advanced Science, 2023 PRDM16 (PR domain containing protein 16) serves as a dominant activator of brown and beige adipocyte. However, mechanisms underlying the regulation of PRDM16 expression are incompletely understood.
Shiting Zhao +15 more
doaj +2 more sources
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism. [PDF]
, 2019 Prolonged cold exposure stimulates the recruitment of beige adipocytes within white adipose tissue. Beige adipocytes depend on mitochondrial oxidative phosphorylation to drive thermogenesis.
Lee, Sanghoon +7 more
core +5 more sources
Fighting obesity by targeting factors regulating beige adipocytes. [PDF]
Current Opinion in Clinical Nutrition & Metabolic Care, 2018 Purpose of reviewThe current review provides an update on secreted factors and mechanisms that promote a thermogenic program in beige adipocytes, and their potential roles as therapeutic targets to fight obesity.Recent findingsWe outline recent studies ...
Koliwad, Suneil K +2 more
core +6 more sources
Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4. [PDF]
Diabetes, 2017 Uncoupling protein 1+ beige adipocytes are dynamically regulated by environment in rodents and humans; cold induces formation of beige adipocytes, whereas warm temperature and nutrient excess lead to their disappearance. Beige adipocytes can form through
Chawla, Ajay +6 more
core +6 more sources
ESRRG and PERM1 Govern Mitochondrial Conversion in Brite/Beige Adipocyte Formation [PDF]
Frontiers in Endocrinology, 2020 When exposed to cold temperatures, mice increase their thermogenic capacity by an expansion of brown adipose tissue mass and the formation of brite/beige adipocytes in white adipose tissue depots.
Sebastian Müller +8 more
doaj +2 more sources