Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte [PDF]
Advanced Science, 2023 PRDM16 (PR domain containing protein 16) serves as a dominant activator of brown and beige adipocyte. However, mechanisms underlying the regulation of PRDM16 expression are incompletely understood.
Hannah Xiaoyan Hui
exaly +3 more sources
A Method to Induce Brown/Beige Adipocyte Differentiation from Murine Preadipocytes [PDF]
Bio-Protocol, 2021 Adipocytes exhibit different morphological and functional characteristics, depending on their anatomical location, developmental origin, and stimulus. While white adipocytes tend to accumulate energy as triglycerides, brown and beige adipocytes tend to ...
Andréa Rocha +3 more
doaj +2 more sources
In vitro analyses of paracrine effects of murine classically activated macrophage on beige adipocyte metabolism [PDF]
STAR Protocols, 2022 Summary: The communication between macrophage and adipocyte plays a critical role in the initiation and development of metabolic inflammation, which is difficult to study in vivo.
Jingfei Yao, Dongmei Wu, Yifu Qiu
doaj +2 more sources
Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression [PDF]
PLoS Genetics, 2017 Given the relevance of beige adipocytes in adult humans, a better understanding of the molecular circuits involved in beige adipocyte biogenesis has provided new insight into human brown adipocyte biology. Genetic mutations in SLC39A13/ZIP13, a member of
Tsutomu Sasaki +2 more
exaly +2 more sources
Identification of an alternative ligand‐binding pocket in peroxisome proliferator‐activated receptor gamma and its correlated selective agonist for promoting beige adipocyte differentiation [PDF]
MedCommThe pharmacological activation of peroxisome proliferator‐activated receptor gamma (PPARγ) is a convenient and promising strategy for promoting beige adipocyte biogenesis to combat obesity‐related metabolic disorders.
Qiang Tian +8 more
doaj +2 more sources
SIRT7 Inhibits Adipose Tissue Browning Through Deacetylation of PPARγ2 at K382 [PDF]
CellsAdipose tissue (AT) browning is an inducible cellular phenomenon that promotes lipid oxidation to increase energy expenditure, reducing adiposity. Various transcription regulators involved in the AT browning process have been reported, but their complex ...
Avizit Das +8 more
doaj +2 more sources
Towards a Better Understanding of Beige Adipocyte Plasticity [PDF]
Cells, 2019 Biao Wang, Esther Paulo Mirasol
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Neonatal intake of Omega-3 fatty acids enhances lipid oxidation in adipocyte precursors
iScience, 2023 Summary: Establishing metabolic programming begins during fetal and postnatal development, and early-life lipid exposures play a critical role during neonatal adipogenesis. We define how neonatal consumption of a low omega-6 to −3 fatty acid ratio (n6/n3
Rohan Varshney +14 more
doaj +1 more source
The Beige Adipocyte as a Therapy for Metabolic Diseases [PDF]
International Journal of Molecular Sciences, 2019 Fernando Lizcano, Fernando Lizcano
exaly +2 more sources
Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance [PDF]
Cell Metabolism, 2016 Kosaku Shinoda +2 more
exaly +2 more sources