Results 21 to 30 of about 7,234 (170)
Spermidine/spermine N1-acetyltransferase-mediated polyamine catabolism regulates beige adipocyte biogenesis [PDF]
Metabolism: Clinical and Experimental, 2018 Xiang Lu, Kamyar Zahedi, Wei Gao
exaly +2 more sources
CD90 Is Dispensable for White and Beige/Brown Adipocyte Differentiation [PDF]
International Journal of Molecular Sciences, 2020 Brown adipose tissue (BAT) is a thermogenic organ in rodents and humans. In mice, the transplantation of BAT has been successfully used to combat obesity and its comorbidities. While such beneficial properties of BAT are now evident, the developmental and cellular origins of brown, beige, and white adipocytes have remained only poorly understood ...
Meike Dahlhaus +15 more
openaire +3 more sources
Effects of exercise on brown and beige adipocytes
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019 Physical exercise leads to beneficial effects in numerous tissues and organ systems and offers protection against obesity and type 2 diabetes. Recent studies have investigated the role of exercise on brown adipose tissue (BAT) and white adipose tissue (WAT), and have indicated marked adaptations to each tissue with exercise.
Dewal, Revati S., Stanford, Kristin I.
openaire +2 more sources
Adipocyte HDAC4 activation leads to beige adipocyte expansion and reduced adiposity. [PDF]
J Endocrinol, 2018 Numerous studies have suggested that beige adipocyte abundance is correlated with improved metabolic performance, but direct evidence showing that beige adipocyte expansion protects animals from the development of obesity is missing. Previously, we have described that the liver kinase b1 (LKB1) regulates beige adipocyte renaissance in subcutaneous ...
Paulo E +4 more
europepmc +6 more sources
Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway
Cell Reports, 2018 Summary: Beige adipocytes are present in white adipose tissue (WAT) and have thermogenic capacity to orchestrate substantial energy metabolism and counteract obesity.
Xing Zhang +16 more
doaj +1 more source
Neural control of white, beige and brown adipocytes [PDF]
International Journal of Obesity Supplements, 2015 Reports of brown-like adipocytes in traditionally white adipose tissue (WAT) depots occurred ~30 years ago, but interest in white adipocyte 'browning' only has gained attention more recently. We integrate some of what is known about the sympathetic nervous system (SNS) innervation of WAT and brown adipose tissue (BAT) with the few studies focusing on ...
T J, Bartness, V, Ryu
openaire +2 more sources
Beige Fat, Adaptive Thermogenesis, and Its Regulation by Exercise and Thyroid Hormone
Biology, 2019 While it is now understood that the proper expansion of adipose tissue is critically important for metabolic homeostasis, it is also appreciated that adipose tissues perform far more functions than simply maintaining energy balance.
Kevin J. Phillips
doaj +1 more source
The Common and Distinct Features of Brown and Beige Adipocytes [PDF]
Trends in Endocrinology & Metabolism, 2018 Two types of thermogenic fat cells, brown adipocytes and beige adipocytes, play a key role in the regulation of systemic energy homeostasis in mammals. Both brown fat and beige fat possess thermogenic properties in addition to common morphological and biochemical characteristics, including multilocular lipid droplets and cristae-dense mitochondria ...
Kenji, Ikeda +2 more
openaire +2 more sources
Sympathetic nerve innervation is required for beigeing in white fat
Physiological Reports, 2019 It is increasingly recognized that activation of beige adipocyte thermogenesis by pharmacological or genetic approaches increases energy expenditure and alleviates obesity.
Qiang Cao +4 more
doaj +1 more source
Molecular Metabolism, 2016 Objective: Adipose tissue relies on lipid droplet (LD) proteins in its role as a lipid-storing endocrine organ that controls whole body metabolism.
Marina T. DiStefano +11 more
doaj +1 more source