Results 131 to 140 of about 38,129 (248)

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. [PDF]

, 2019
Branched-chain amino acid (BCAA; valine, leucine and isoleucine) supplementation is often beneficial to energy expenditure; however, increased circulating levels of BCAA are linked to obesity and diabetes.
A Balkow, A Bartelt, AM Cypess, Ayano Ueno, B Tasic, C Jang, Carlos Henrique Sponton, CB Newgard, CB Newgard, CJ Lynch, CR Green, CT Ferrara, DE Lackey, EG Sustarsic, F Palmieri, Francis C. Szoka, H Ohno, Haruya Takahashi, Hiroko Maki, Homa Majd, Huixia Li, K Ikeda, K Shinoda, Kaori Igarashi, Kazuki Tajima, KC Das, Kenji Ikeda, KH Pietiläinen, KM Huffman, Kyeongkyu Kim, LA Gilbert, Labros Sidossis, M Chondronikola, M Rosell, M Saito, M Wallace, MA Herman, Maki Ohishi, Mami Matsushita, Maria Chondronikola, Masayuki Saito, MD Neinast, Michael T. McManus, Mito Kuroda, Momoko Yoneshiro, Olga R. Ilkayeva, P She, Phillip J. White, PJ White, PJ White, Qiang Wang, Rachana N. Pradhan, Robert W. McGarrah, SH Um, Shingo Kajimura, T Li, T Soga, T Soga, T Yoneshiro, Takamasa Ishikawa, Takeshi Yoneshiro, Teruo Kawada, TJ Wang, Tomoyoshi Soga, Tsuyoshi Goto, V Ouellet, Vanille Juliette Greiner, X Kong, Yann Deleye, Yasuo Oguri, Yong Chen, Zachary Brown, Zhipeng Dai   +72 more
core   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
wiley   +1 more source

Adipocyte browning and higher mitochondrial function in peri-adrenal but not subcutaneous fat in pheochromocytoma [PDF]

, 2016
Context: Patients with pheochromocytoma (pheo) show presence of multilocular adipocytes that express uncoupling protein (UCP) 1 within periadrenal (pADR) and omental (OME) fat depots. It has been hypothesized that this is due to adrenergic stimulation
Avital Harari, Betz, Bordicchia, Cannon, Chondronikola, Cypess, Cypess, Cypess, de Jong, Di Franco, Frontini, Giordano, Graeme R. Davies, Harold S. Sacks, Himms-Hagen, Hondares, Huang, Jason Y. Lin, Jespersen, Kajimura, Karen Reue, Kern, Laurent Vergnes, Leibel, Lidell, Masha J. Livhits, Michael E. Symonds, Michael W. Yeh, Nagano, Nedergaard, Patsouris, Petrovic, Plouin, Rogers, Sacks, Seale, Sharp, Shinoda, Sidossis, Stepniakowski, Strack, Svensson, Søndergaard, Ussar, van der Lans, van Marken Lichtenbelt, Virtanen, Waldén, Wu   +48 more
core   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Functional Implications of DNA Methylation in Adipose Biology. [PDF]

, 2019
The twin epidemics of obesity and type 2 diabetes (T2D) are a serious health, social, and economic issue. The dysregulation of adipose tissue biology is central to the development of these two metabolic disorders, as adipose tissue plays a pivotal role ...
Kang, Sona, Ma, Xiang
core  

A Literature Review On Intermittent Fasting [PDF]

, 2020
Intermittent fasting has been instructed in the Bible as an implied part of daily living. This paper has reviewed the physical benefits of intermittent fasting. In healthy test subjects, it has led to higher levels of autophagy, gut health, and lifespan.
Carrero, Kylie
core   +1 more source

Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism. [PDF]

, 2019
Prolonged cold exposure stimulates the recruitment of beige adipocytes within white adipose tissue. Beige adipocytes depend on mitochondrial oxidative phosphorylation to drive thermogenesis.
Lee, Sanghoon, Loft, Anne, Mandrup, Susanne, Pearson, Stephanie, Rajbhandari, Prashant, Simcox, Judith, Tontonoz, Peter, Villanueva, Claudio J   +7 more
core   +3 more sources

FGF2 disruption enhances thermogenesis in brown and beige fat to protect against obesity and hepatic steatosis

bioRxiv, 2020
Since brown and beige fat expend energy in the form of heat via non-shivering thermogenesis, identifying key regulators of thermogenic functions represents a major goal for development of potential therapeutic avenues for obesity and associated disorders.
Haifang Li, Xinzhi Zhang, Cheng-Di Huang, Huan Liu, Shuang Liu, Qiang Zhang, Meijun Dong, Mengjie Hou, Yiming Liu, Hai Lin   +9 more
semanticscholar   +1 more source

Brown adipose tissue activity impacts systemic lactate clearance in male mice

The Journal of Physiology, EarlyView.
Abstract figure legend Using lactate tolerance tests and in vivo 13C isotopic tracing experiments performed in male mice housed at different temperatures, this study demonstrates that the state of activation of non‐shivering thermogenesis in brown adipose tissue (BAT) impacts systemic lactate metabolism.
Rémi Montané, Yannick Jeanson, Damien Lagarde, Spiro Khoury, Léana Porcher‐Bibes, Jean Nakhle, Marie Sallese, Mélissa Parny, Isabelle Raymond‐Letron, Emma Huard, Raphael Alves de Souza, Anne Galinier, Luc Pellerin, Anne‐Karine Bouzier Sore, Jean‐Philippe Pradère, Cédric Moro, Louis Casteilla, Armelle Yart, Cédric Dray, Jean‐Charles Portais, Isabelle Ader, Audrey Carriere   +21 more
wiley   +1 more source

Decoding temporal thermogenesis: coregulator selectivity and transcriptional control in brown and beige adipocytes

Adipocyte
In mammals, brown adipose tissue (BAT) and beige adipocytes in white adipose tissue (WAT) play pivotal roles in maintaining body temperature and energy metabolism.
Yong Geun Jeon, Sun Won Kim, Jae Bum Kim
doaj   +1 more source