Results 141 to 150 of about 10,902 (169)
Multifaceted Roles of Beige Fat in Energy Homeostasis Beyond UCP1.
Endocrinology, 2018 Sponton CH, Kajimura S.
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HDAC3-Selective Inhibition Activates Brown and Beige Fat Through PRDM16.
Endocrinology, 2018 Liao J +6 more
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Control of brown and beige fat development [PDF]
Nature Reviews Molecular Cell Biology, 2016 Brown and beige adipocytes expend chemical energy to produce heat and are therefore important in regulating body temperature and body weight. Brown adipocytes develop in discrete and relatively homogenous depots of brown adipose tissue, whereas beige adipocytes are induced to develop in white adipose tissue in response to certain stimuli - notably ...
Patrick Seale +2 more
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Morphogenetics in brown, beige and white fat development [PDF]
Adipocyte, 2016 Brown and beige (or brite) fat cells are capable of evoking non-shivering thermogenesis in response to cold and β-adrenergic stimulation. By metabolizing lipids and carbohydrate via uncoupled respiration these cells directly convert energy to heat.
Stephen Farmer, Jean Z Lin
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Brown and beige fat: development, function and therapeutic potential [PDF]
Nature Medicine, 2013 Adipose tissue, best known for its role in fat storage, can also suppress weight gain and metabolic disease through the action of specialized, heat-producing adipocytes. Brown adipocytes are located in dedicated depots and express constitutively high levels of thermogenic genes, whereas inducible 'brown-like' adipocytes, also known as beige cells ...
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Science Signaling, 2022
A ubiquitin E3 ligase complex limits the generation of beige fat.
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A ubiquitin E3 ligase complex limits the generation of beige fat.
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MicroRNAs in brown and beige fat
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019Brown adipose tissue (BAT) dissipates energy as heat and its activity correlates with leanness in human adults. Understanding the mechanisms behind the activation of BAT and the process of "browning", i.e. the appearance of inducible brown adipocytes called beige or brite (brown-in-white) cells in white adipose tissue (WAT), is of great interest for ...
Deborah, Goody, Alexander, Pfeifer
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Regulation of brown and beige fat by microRNAs
Pharmacology & Therapeutics, 2017MicroRNAs (miRNAs) are small non-coding RNA molecules consisting of approximately 20 to 22 nucleotides. They play a very important role in the regulation of gene expression. miRNAs can be found in different species and a variety of organs and tissues including adipose tissue.
Yong, Chen +2 more
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Deriving functional beige fat from capillaries
Nature Medicine, 2016In a recent study, beige adipocytes were derived from the capillaries of human subcutaneous adipose tissue. When implanted into mice, these cells enhanced glucose tolerance, thus providing evidence for their potential therapeutic use.
Vanessa, Pellegrinelli +1 more
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Brown and beige fat: From molecules to physiology
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019The recent re-discovery of brown adipose tissue (BAT) and even more recent discovery of the browning of white adipose tissue (WAT) in humans have generated intense scientific interest in the role of adipose tissue as potential target against obesity and its metabolic complications.
Maria, Chondronikola, Labros S, Sidossis
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