The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function [PDF]
IntroductionBrown adipocytes produce heat through non shivering thermogenesis (NST). To adapt to temperature cues, they possess a remarkably dynamic metabolism and undergo substantial cellular remodeling.
Zeynep Koçberber +5 more
doaj +2 more sources
A key role for P2RX5 in brown adipocyte differentiation and energy homeostasis [PDF]
Brown adipocytes are defined based on a distinct morphology and genetic signature that includes, amongst others, the expression of the Purinergic 2 Receptor X5 (P2RX5).
Maria Razzoli +10 more
doaj +2 more sources
Collagen-derived dipeptide prolyl-hydroxyproline cooperates with Foxg1 to activate the PGC-1α promoter and induce brown adipocyte-like phenotype in rosiglitazone-treated C3H10T1/2 cells [PDF]
BackgroundThe global obesity epidemic is a significant public health issue, often leading to metabolic disorders such as diabetes and cardiovascular diseases.
Kaho Nomura +9 more
doaj +2 more sources
Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation
Objective: Long noncoding RNAs (lncRNAs) are emerging as important regulators of diverse biological processes. Recent work has demonstrated that the inducible lncRNA Blnc1 stimulates thermogenic gene expression during brown and beige adipocyte ...
Jiandie Lin, Xuyun Zhao, Lin Mi
exaly +3 more sources
Control of murine brown adipocyte development by GATA6 [PDF]
Patrick Seale
exaly +2 more sources
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice
Using a number of cell biological and statistical methods we identify and characterize EIF5, TCF25 and BIN1 as markers for individual brown adipocyte subtypes in C57BL/6J mice.
Ruth Karlina +23 more
doaj +1 more source
In sheep industry, hypothermia caused by insufficient brown adipose tissue (BAT) deposits is one of the major causes of lamb deaths. Enhancing the formation and function of BAT in neonatal lamb increases thermogenesis and hence reduces economic losses ...
Xu-Yang Gao +6 more
doaj +1 more source
Brown Adipose Tissue Heterogeneity, Energy Metabolism, and Beyond
Brown adipocyte in brown adipose tissue (BAT) specializes in expending energy through non-shivering thermogenesis, a process that produces heat either by uncoupling protein 1 (UCP1) dependent uncoupling of mitochondrial respiration or by UCP1 independent
Abhijit Babaji Shinde +3 more
doaj +1 more source
Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat
Brown adipocytes contribute to energy balance, and adipocyte development and brown adipocyte thermogenesis are in part regulated by epigenetic modifications.
Fenfen Li +11 more
doaj +1 more source
Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase. [PDF]
BackgroundBrown adipocytes play an important role in regulating the balance of energy, and as such, there is a strong correlation between obesity and the amount of brown adipose tissue.
Hye-Ryung Choi +8 more
doaj +1 more source

