The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function [PDF]
Frontiers in Endocrinology, 2023 IntroductionBrown adipocytes produce heat through non shivering thermogenesis (NST). To adapt to temperature cues, they possess a remarkably dynamic metabolism and undergo substantial cellular remodeling.
Zeynep Koçberber +5 more
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A key role for P2RX5 in brown adipocyte differentiation and energy homeostasis [PDF]
AdipocyteBrown adipocytes are defined based on a distinct morphology and genetic signature that includes, amongst others, the expression of the Purinergic 2 Receptor X5 (P2RX5).
Maria Razzoli +10 more
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Collagen-derived dipeptide prolyl-hydroxyproline cooperates with Foxg1 to activate the PGC-1α promoter and induce brown adipocyte-like phenotype in rosiglitazone-treated C3H10T1/2 cells [PDF]
Frontiers in NutritionBackgroundThe global obesity epidemic is a significant public health issue, often leading to metabolic disorders such as diabetes and cardiovascular diseases.
Kaho Nomura +9 more
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Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation
Cell Reports, 2019 Summary: Browning induction or transplantation of brown adipose tissue (BAT) or brown/beige adipocytes derived from progenitor or induced pluripotent stem cells (iPSCs) can represent a powerful strategy to treat metabolic diseases.
Steve Lancel +2 more
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Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation
Molecular Metabolism, 2017 Objective: Long noncoding RNAs (lncRNAs) are emerging as important regulators of diverse biological processes. Recent work has demonstrated that the inducible lncRNA Blnc1 stimulates thermogenic gene expression during brown and beige adipocyte ...
Jiandie Lin, Xuyun Zhao, Lin Mi
exaly +3 more sources
Control of murine brown adipocyte development by GATA6 [PDF]
Developmental Cell, 2023 Patrick Seale
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Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice
Life Science Alliance, 2021 Using a number of cell biological and statistical methods we identify and characterize EIF5, TCF25 and BIN1 as markers for individual brown adipocyte subtypes in C57BL/6J mice.
Ruth Karlina +23 more
doaj +1 more source
Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism [PDF]
Cell Reports, 2021 Youngho Seo +2 more
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Frontiers in Veterinary Science, 2021 In sheep industry, hypothermia caused by insufficient brown adipose tissue (BAT) deposits is one of the major causes of lamb deaths. Enhancing the formation and function of BAT in neonatal lamb increases thermogenesis and hence reduces economic losses ...
Xu-Yang Gao +6 more
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Brown Adipose Tissue Heterogeneity, Energy Metabolism, and Beyond
Frontiers in Endocrinology, 2021 Brown adipocyte in brown adipose tissue (BAT) specializes in expending energy through non-shivering thermogenesis, a process that produces heat either by uncoupling protein 1 (UCP1) dependent uncoupling of mitochondrial respiration or by UCP1 independent
Abhijit Babaji Shinde +3 more
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