Results 1 to 10 of about 1,446,812 (280)
Stress-inducible IL-6 is regulated by KLF7 in brown adipocytes [PDF]
Heliyon, 2023 Stress-inducible interleukin 6 (IL-6) is generated in brown adipocytes via beta-3 adrenergic receptor (ADRB3) signaling, which is necessary in stress hyperglycemia, the kind of metabolic adaptation enabling “fight or flight” response by means of liver ...
Yihan Tang +11 more
doaj +2 more sources
Direct Evidence of Brown Adipocytes in Different Fat Depots in Children
PLoS ONE, 2015 Recent studies suggested the persistence of brown adipocytes in adult humans, as opposed to being exclusively present in infancy. In this study, we investigated the presence of brown-like adipocytes in adipose tissue (AT) samples of children and ...
Antje Körner +2 more
exaly +3 more sources
A Genetic Model to Study the Contribution of Brown and Brite Adipocytes to Metabolism
Cell Reports, 2020 Summary: UCP1-dependent thermogenesis is studied to define new strategies to ameliorate obesity and type 2 diabetes; however, animal models are mostly limited to germline mutations of UCP1, which can effect adaptive changes in UCP1-independent pathways ...
Wenfei Sun +2 more
exaly +3 more sources
Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo
Molecular Metabolism, 2017 Objective: Previous work has suggested that white adipocytes may also show a mammary luminal secretory cell phenotype during lactation. The capacity of brown and beige/brite adipocytes to display a mammary cell phenotype and the levels at which they ...
Speakman John, Elżbieta Król
exaly +3 more sources
Commitment of adipose-resident c-kit+ progenitors to brown adipocytes contributes to adipose tissue homeostasis and remodeling [PDF]
Nature CommunicationsThe global incidence of obesity-related metabolic disorders and their comorbidities continue to increase along with a demand for innovative therapeutic interventions.
Qishan Chen +11 more
doaj +2 more sources
Molecular Metabolism, 2021 Objective: Recent studies indicate that brown adipose tissue, in addition to its role in thermogenesis, has a role in the regulation of whole-body metabolism.
Belén Picatoste +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Brown adipose tissue (BAT) is a specialized tissue that regulates non-shivering thermogenesis. In Syrian hamsters, interscapular adipose tissue is composed primarily of white adipocytes at birth, which is converted to BAT through the proliferation and ...
Junnosuke Mae +6 more
doaj +1 more source
Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice. [PDF]
PLoS ONE, 2013 Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura +6 more
doaj +1 more source
Identification of Biochemical Differences in White and Brown Adipocytes Using FTIR Spectroscopy
Applied Sciences, 2022 This study was conducted to investigate the developmental characteristics of adipocytes and to identify selectively white and brown adipocytes through Fourier transform infrared (FTIR) spectroscopy.
DongHyun Shon +3 more
doaj +1 more source
The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function
Frontiers in Endocrinology, 2023 IntroductionBrown adipocytes produce heat through non shivering thermogenesis (NST). To adapt to temperature cues, they possess a remarkably dynamic metabolism and undergo substantial cellular remodeling.
Zeynep Koçberber +5 more
doaj +1 more source