Results 41 to 50 of about 39,242 (266)
Frontiers in Physiology, 2021 The mammalian target of rapamycin (mTOR) is an important protein kinase that senses changes in extracellular and intracellular energy levels and plays a key role in regulating energy metabolism.
Bahetiyaer Huwatibieke +10 more
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Transcriptional fingerprinting of "browning" white fat identifies NRG4 as a novel adipokine [PDF]
, 2014 Brown adipocytes help to maintain body temperature by the expression of a unique set of genes that facilitate cellular metabolic events including uncoupling protein 1-dependent thermogenesis.
Christian, Mark, Christian, M
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Loading and firing the brown adipocyte [PDF]
Adipocyte, 2017 Brown adipose tissue (BAT) is specialized to both store and expend chemical energy making it an ideal therapeutic target for various metabolic diseases. Fatty acids derived from lipid droplets within brown adipocytes acting on mitochondrial uncoupling protein 1 (UCP1) were long thought to be essential for non-shivering thermogenesis. Here, the roles of
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Bioactive Compounds and Adipocyte Browning Phenomenon
Current Issues in Molecular Biology, 2022 Overweight and obesity have become worldwide health issues in most countries. Current strategies aimed to prevent or reduce overweight and obesity have mainly focused on the genes and molecular mechanisms that give the functional characteristics to different types of adipose tissue.
Josué Manríquez-Núñez +1 more
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Short-chain fatty acid acetate stimulates adipogenesis and mitochondrial biogenesis via GPR43 in brown adipocytes [PDF]
, 2016 Short-chain fatty acids play crucial roles in a range of physiological functions. However, the effects of short-chain fatty acids on brown adipose tissue have not been fully investigated.
GK Dimitriadis (7772033) +45 more
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P2X₅ receptor is functionally expressed on mouse brown adipocyte and can be a cell surface marker [PDF]
, 2016 Brown adipocytes expressed a large variety of purinergic receptor subtypes. We investigated about the expression of P2X5 receptor subtype among purinergic receptor subtypes expressed in mouse adipose tissue.Ca2+ imaging showed that applied 10 μM ATP or 1
ハヤト, リョウタロウ +4 more
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Adipocyte, 2022 Neuroblastoma (NB) is an embryonic malignant tumour of the sympathetic nervous system, and current research shows that activation of brown adipose tissue accelerates cachexia in cancer patients.
Zhijuan Ge +4 more
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The Role of Solute Carrier Transporters in Brown Adipocytes [PDF]
, 2023 Adipose tissues, including white adipose tissue (WAT) and brown adipose tissue (BAT), play a critical role in regulating insulin sensitivity and energy homeostasis, making them potential targets for clinical interventions to fight against obesity.
Sucipto, Abby Kurniawati
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Effects of exercise on brown and beige adipocytes
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019 Physical exercise leads to beneficial effects in numerous tissues and organ systems and offers protection against obesity and type 2 diabetes. Recent studies have investigated the role of exercise on brown adipose tissue (BAT) and white adipose tissue (WAT), and have indicated marked adaptations to each tissue with exercise.
Dewal, Revati S., Stanford, Kristin I.
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Adrenoceptors in white, brown, and brite adipocytes [PDF]
British Journal of Pharmacology, 2019 Adrenoceptors play an important role in adipose tissue biology and physiology that includes regulating the synthesis and storage of triglycerides (lipogenesis), the breakdown of stored triglycerides (lipolysis), thermogenesis (heat production), glucose metabolism, and the secretion of adipocyte‐derived hormones that can control whole‐body energy ...
Bronwyn A. Evans +3 more
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