Results 201 to 210 of about 38,179 (226)
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MicroRNAs in brown and beige fat

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019
Brown adipose tissue (BAT) dissipates energy as heat and its activity correlates with leanness in human adults. Understanding the mechanisms behind the activation of BAT and the process of "browning", i.e. the appearance of inducible brown adipocytes called beige or brite (brown-in-white) cells in white adipose tissue (WAT), is of great interest for ...
Deborah, Goody, Alexander, Pfeifer
openaire   +2 more sources

Regulation of brown and beige fat by microRNAs

Pharmacology & Therapeutics, 2017
MicroRNAs (miRNAs) are small non-coding RNA molecules consisting of approximately 20 to 22 nucleotides. They play a very important role in the regulation of gene expression. miRNAs can be found in different species and a variety of organs and tissues including adipose tissue.
Yong, Chen   +2 more
openaire   +2 more sources

Brown and beige fat: From molecules to physiology

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019
The recent re-discovery of brown adipose tissue (BAT) and even more recent discovery of the browning of white adipose tissue (WAT) in humans have generated intense scientific interest in the role of adipose tissue as potential target against obesity and its metabolic complications.
Maria, Chondronikola, Labros S, Sidossis
openaire   +2 more sources

Common traits between the beige fat-inducing stimuli

Current Opinion in Cell Biology, 2018
Adipose tissues play an essential role in regulating the metabolic homeostasis and can be found in almost all parts of the body. Excessive adiposity leads to obesity and can contribute to metabolic and other disorders. Adipocytes show remarkable plasticity in their function, which can be pushed toward energy storage, or energy expenditure-a `browning ...
Stojanovic, Ozren   +2 more
openaire   +3 more sources

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis [PDF]

open access: yesCell, 2015
Type 2 innate lymphoid cells (ILC2s), an innate source of the type 2 cytokines interleukin (IL)-5 and -13, participate in the maintenance of tissue homeostasis. Although type 2 immunity is critically important for mediating metabolic adaptations to environmental cold, the functions of ILC2s in beige or brown fat development are poorly defined.
Yifu Qiu   +2 more
exaly   +5 more sources

Parkin mediates mitophagy during beige-to-white fat conversion

Science Signaling, 2018
Blocking Parkin-mediated mitophagy may help beige fat retain its thermogenic properties (Lu et al ., in 24 April 2018 issue).
Shireen A. Sarraf, Richard J. Youle
openaire   +2 more sources

Dietary fatty acids activate or deactivate brown and beige fat

Life Sciences, 2023
Brown adipose tissue (BAT) and beige fat have been documented to rapidly consume fatty acids (FAs) rather than deposit of lipid, and they have high capacity to dissipate energy via nonshivering thermogenesis, making BAT and beige fat potential organs to fight obesity and related chronic diseases.
Min, Jia   +3 more
openaire   +2 more sources

[Histamine stimulates thermogenesis of brown and beige fat].

Sheng li xue bao : [Acta physiologica Sinica], 2021
β3-adrenergic agonists induce adaptive thermogenesis and promote beiging of white fat. However, it remains unclear which metabolites mediate the stimulatory effects of β3-adrenergic agonists on thermogenesis of brown and beige fat. In this study, adipose tissue was isolated from 8-week-old C57/BL6J male mice by intraperitoneal administration of β3 ...
Yue-Yao, Feng   +2 more
openaire   +1 more source

Econutrition, brown and beige fat tissue and obesity.

Asia Pacific journal of clinical nutrition, 2021
Obesity is caused by excessive fat accumulation or abnormal fat distribution and has become one of the biggest health challenges worldwide. Considering the high thermogenic ability of brown fat tissue (BAT) and the plasticity of fat tissue, to induce the browning of white fat tissue (WAT), so increasing BAT activity provides an attractive option for ...
Kelei, Li   +3 more
openaire   +1 more source

Germinated soy germ extract ameliorates obesity through beige fat activation

Food & Function, 2019
Germinated soy germ extract ameliorates diet-induced obesity via inhibition of adipogenesis and conversion/activation of beige fat.
Han-Jun Kim   +7 more
openaire   +2 more sources

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