Results 211 to 220 of about 38,129 (248)
Control of brown and beige fat development [PDF]
Nature Reviews Molecular Cell Biology, 2016 Brown and beige adipocytes expend chemical energy to produce heat and are therefore important in regulating body temperature and body weight. Brown adipocytes develop in discrete and relatively homogenous depots of brown adipose tissue, whereas beige adipocytes are induced to develop in white adipose tissue in response to certain stimuli - notably ...
Wenshan Wang, Patrick Seale
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Journal of Visualized Experiments, 2023
Clustered regularly interspaced short palindromic repeats (CRISPR) technology has prompted a revolution in biology, and recent tools have been applied far beyond the originally described gene editing.
Fernando Valdivieso-Rivera +2 more
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Clustered regularly interspaced short palindromic repeats (CRISPR) technology has prompted a revolution in biology, and recent tools have been applied far beyond the originally described gene editing.
Fernando Valdivieso-Rivera +2 more
semanticscholar +1 more source
Science Signaling, 2022
A ubiquitin E3 ligase complex limits the generation of beige fat.
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A ubiquitin E3 ligase complex limits the generation of beige fat.
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Nature Medicine, 2017 Uncoupling protein 1 (UCP1) plays a central role in nonshivering thermogenesis in brown fat; however, its role in beige fat remains unclear. Here we report a robust UCP1-independent thermogenic mechanism in beige fat that involves enhanced ATP-dependent ...
Takeshi Yoneshiro +2 more
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Deriving functional beige fat from capillaries [PDF]
Nature Medicine, 2016 In a recent study, beige adipocytes were derived from the capillaries of human subcutaneous adipose tissue. When implanted into mice, these cells enhanced glucose tolerance, thus providing evidence for their potential therapeutic use.
Antonio Vidal-Puig +2 more
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MicroRNAs in brown and beige fat
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019Brown adipose tissue (BAT) dissipates energy as heat and its activity correlates with leanness in human adults. Understanding the mechanisms behind the activation of BAT and the process of "browning", i.e. the appearance of inducible brown adipocytes called beige or brite (brown-in-white) cells in white adipose tissue (WAT), is of great interest for ...
Alexander Pfeifer, Deborah Goody
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Regulation of brown and beige fat by microRNAs
Pharmacology & Therapeutics, 2017MicroRNAs (miRNAs) are small non-coding RNA molecules consisting of approximately 20 to 22 nucleotides. They play a very important role in the regulation of gene expression. miRNAs can be found in different species and a variety of organs and tissues including adipose tissue.
Alexander Pfeifer, Yong Chen, Ruping Pan
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