Results 51 to 60 of about 1,296,584 (365)
Belonging nowhere: Shenaz Patel’s Le Silence des Chagos [PDF]
, 2018 This chapter explores how, as depicted in Patel’s 2005 novel, the notion of belonging, in both its politico-legal and its emotional senses, is central to all aspects of the Chagos islanders’ long-silenced story – to their original expulsion; to their on ...
Waters, Julia
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HIMALAYA, 2020 In Nepal, ethnicity is often constituted through ritual practice. If ritual participation is a key way of exercising membership in an ethnic group, how might Christians--who no longer participate in many community rituals--demonstrate their belonging in ...
Victoria M. Dalzell
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Belonging to the moment: Carl de Souza's Les Jours Kaya [PDF]
, 2018 This chapter examines Carl de Souza’s fictional depiction of the 1999 Kaya riots in relation to Frantz Fanon’s theory of anti-colonial violence, as the novel attempts to give fictional form to both the destructive and creative dimensions of the violence.
Waters, Julia
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The concept of belonging has grown in prominence in research and policy relating to new arrivals from refugee and asylum-seeking backgrounds. Arguably, belonging is replacing integration and inclusion as the panacea to perceived problems associated with ...
McIntyre, Joanna
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Weaving together: narratives of home, exile and belonging [PDF]
, 2021 Art, Borders and Belonging: On Home and Migration investigates how three associated concepts-house, home and homeland-are represented in contemporary global art.
Photiou, Maria
core
Scientific ReportsAn innovative Deep Cross-Modal Emotional Memory Network (DCM-EMNet) and an Adaptive Multi-source Heterogeneous Transfer Learning Framework (AMS-HTLF) are proposed in this paper.
Xiaofen Zhao, Jingchao Liu, Lei Lin
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source