Results 141 to 150 of about 2,472,934 (283)

Benefit-risk assessment of sonidegib and vismodegib in the treatment of locally advanced basal cell carcinoma. [PDF]

Drugs Context, 2022
García Ruiz AJ, García-Agua Soler N, Herrera Acosta E, Zalaudek I, Malvehy J.   +4 more
europepmc   +1 more source

Prevalence of nutrition risk and associated social risk factors in community living older adults in the New Zealand Health, Work and Retirement Study : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Nutrition and Dietetics at Massey University, Auckland, New Zealand [PDF]

, 2017
Background: The New Zealand population is ageing as a result of declining mortality and birth rates. In order for older adults to remain in optimal health, good nutrition is vital.
Tkatch, Melaney Tema
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Benefit/risk assessment in clinical research

Journal of the American College of Cardiology, 1988
Kowey, Peter R., Friehlng, Ted D., Marinchak, Roger A.   +2 more
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Dynamics of Patient-Based Benefit-Risk Assessment of Medicines in Chronic Diseases: A Systematic Review. [PDF]

Patient Prefer Adherence, 2022
El Masri H, McGuire TM, van Driel ML, Benham H, Hollingworth SA.   +4 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

A Brighton Collaboration standardized template with key considerations for a benefit/risk assessment for the Medigen COVID-19 protein vaccine. [PDF]

Vaccine, 2023
Estephan L, Liu LT, Lien CE, Smith ER, Gurwith M, Chen RT, Benefit-Risk Assessment of VAccines by TechnolOgy Working Group (BRAVATO ex-V3SWG).   +6 more
europepmc   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Benefit-risk assessment of COVID-19 vaccine, mRNA (Comirnaty) for age 16-29 years. [PDF]

Vaccine, 2022
Funk PR, Yogurtcu ON, Forshee RA, Anderson SA, Marks PW, Yang H.   +5 more
europepmc   +1 more source