Structured Benefit-Risk Assessment of a New Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) in Individuals Ages 12 Months and Older. [PDF]
Infect Dis Ther, 2023 Neveu D +6 more
europepmc +1 more source
Exposure and risk assessment of dioxins and PCBs in humans
, 2010 The research described in this thesis was conducted to address health risks associated with occupational exposure to chlorophenoxy herbicides and dioxins (especially TCDD), with a special focus on specific health outcomes (cause specific mortality and ...
Dep IRAS +2 more
core
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Benefit-risk assessment of sonidegib and vismodegib in the treatment of locally advanced basal cell carcinoma. [PDF]
Drugs Context, 2022 García Ruiz AJ +4 more
europepmc +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
Risk-benefit assessment of ivabradine in the treatment of chronic heart failure
Drug, Healthcare and Patient Safety, 2014 Irmina Urbanek, Krzysztof Kaczmarek, Iwona Cygankiewicz, Pawel PtaszynskiDepartment of Electrocardiology, Chair of Cardiology and Cardiosurgery, Medical University, Lodz, PolandAbstract: Heart rate is not only a major risk marker in heart failure but ...
Urbanek I +3 more
doaj
Dynamics of Patient-Based Benefit-Risk Assessment of Medicines in Chronic Diseases: A Systematic Review. [PDF]
Patient Prefer Adherence, 2022 El Masri H +4 more
europepmc +1 more source
A state-of-the-art multi-criteria model for drug benefit-risk analysis
Drug benefit-risk analysis is based on firm clinical evidence related to various safety and efficacy outcomes, such as tolerability, treatment response, and adverse events.
Postmus, D. +3 more
core