Results 141 to 150 of about 1,384,561 (311)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

The environmental impact of Swedish adolescents’ diets

Environmental Research: Food Systems
Adolescence is a critical life stage characterised by rapid development and openness to change. Habits formed during adolescence tend to progress into adulthood, making adolescents a key target group for interventions promoting long-term sustainable ...
Anna Karin Lindroos, Anna Winkvist, Elin Röös, Elinor Hallström   +3 more
doaj   +1 more source

Total mercury and fatty acids content in selected fish marketed in Quito - Ecuador. A benefit-risk assessment. [PDF]

Toxicol Rep, 2023
Yánez-Jácome GS, Romero-Estévez D, Vélez-Terreros PY, Navarrete H.   +3 more
europepmc   +1 more source

Regulatory benefit-risk assessment

, 2013
De beoordeling van nieuwe geneesmiddelen is erop gericht alleen veilige, effectieve en kwalitatief hoogwaardige geneesmiddelen toe te laten tot de markt. UMCG-promovendus Arna Arnardóttir onderzocht hoe registratieautoriteiten een passend evenwicht vinden tussen voordelen en risico’s.
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Quantitative Benefit-Risk Assessment of COVID-19 Vaccines Using the Multi-Criteria Decision Analysis. [PDF]

Vaccines (Basel), 2022
Son KH, Kwon SH, Na HJ, Baek Y, Kim I, Lee EK.   +5 more
europepmc   +1 more source

An Analysis of the Government's Proposed Risk Assessment Guidelines

This paper critically reviews the government's proposed risk assessment guidelines. While we believe that such guidelines may be helpful, we make two recommendations that could improve their effectiveness.
Hahn, Robert W., Litan, Robert E.
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Multimethod quantitative benefit-risk assessment of treatments for moderate-to-severe osteoarthritis. [PDF]

Br J Clin Pharmacol, 2022
Mauer J, Bullok K, Watt S, Whalen E, Russo L, Junor R, Markman J, Hauber B, Tervonen T.   +8 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source