Results 51 to 60 of about 3,493,028 (307)

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Chrysanthemum as a remarkable edible flower resource with anti‐glycation effects: Representative variety differences, phenolic compositions, and the interaction mechanism

Food Frontiers
Various edible chrysanthemum flowers possess different anti‐glycation effects due to various compositions; however, the interaction mechanism is unclear.
Zhangtie Wang, Yuhang Zhu, Minjun Xu, Kejie Peng, Binhai Shi, Yixuan Wang, Qi Chen, Weisu Huang, Yidan Chen, Baiyi Lu   +9 more
doaj   +1 more source

Anwendungsbegleitende Datenerhebungen für die Nutzenbewertung von Arzneimitteln in Deutschland: Warum, wann und wie?

GMS Medizinische Informatik, Biometrie und Epidemiologie
For newly authorised medicinal products with new active substances, a benefit assessment is carried out at the time of their market access in Germany. The subject of this assessment is the question of the additional benefit of the new active substance ...
Kaiser, Thomas, Vervölgy, Volker
doaj   +1 more source

Establishing cost-effectiveness of genetic targeting of cancer therapies\ud [PDF]

, 2008
The clinical benefit of a new genomic instrument, the 70-gene signature\ud for breast cancer patients, is being evaluated in a randomised clinical\ud trial.
Harten, W.H. van, Joore, M.A., Retèl, Valesca P., Rutgers, E.J.Th.   +3 more
core   +2 more sources

Cost of Services and Incentives in the UK Employment Retention and Advancement (ERA) Demonstration: Preliminary Analysis [PDF]

, 2009
This report presents a preliminary analysis of the cost of operating Britain's Employment Retention and Advancement (ERA) demonstration, which is being evaluated though a large-scale randomised control trial.
David Greenberg, Genevieve Knight, Johanna Walter   +2 more
core   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Machbarkeit und Praktikabilität der anwendungsbegleitenden Datenerhebung (AbD) - Erfahrungen, Analysen und Weiterentwicklungsvorschläge

Monitor Versorgungsforschung
Der Gesetzgeber hat mit dem 2019 eingeführten Instrument der anwendungsbegleitenden Datenerhebung (AbD) die Möglichkeit geschaffen, vergleichende Daten in der laufenden Versorgung zu erheben.
Dr. rer. nat. Matthias Wilken, Fabian Berkemeier MSc   +1 more
doaj   +1 more source

Qualitative methods of benefit / risk assessment

Безопасность и риск фармакотерапии, 2022
In this article authors describe some existing methods of benefit / risk assessment.
A. P. Pereverzev, A. N. Mironov, N. D. Bunyatyan, V. K. Lepakhin, B. K. Romanov   +4 more
doaj  

Strategy for communicating benefit-risk decisions: A comparison of regulatory agencies’ publicly available documents

Frontiers in Pharmacology, 2014
The assessment report formats of four major regulatory reference agencies, US Food and Drug Administration, European Medicines Agency, Health Canada, and Australia’s Therapeutic Goods Administration were compared to a benefit-risk (BR) documentation ...
James eLeong Wai Yeen, Sam eSalek, Sam eSalek, Stuart eWalker, Stuart eWalker   +4 more
doaj   +1 more source