Results 101 to 110 of about 6,539 (200)

New horizons for the treatment of severe, eosinophilic asthma: benralizumab, a novel precision biologic

Biologics: Targets & Therapy, 2019
Marco Caminati,1,2 Diego Bagnasco,3 Rachele Vaia,2 Gianenrico Senna11Asthma Center and Allergy Unit, Verona University Hospital, Verona, Italy; 2Department of Medicine, School of Specialization in Allergy and Clinical Immunology, University of Verona ...
Caminati M, Bagnasco D, Vaia R, Senna G
doaj  

Real-world comparative effectiveness of biologic therapies in severe asthma: EU-ADVANTAGE

ERJ Open Research
Background In Europe, although multiple biologics have been approved for the treatment of severe asthma (SA), comparative data from real-world settings remain limited. This study compared the real-world effectiveness of dupilumab with that of omalizumab,
Giorgio Walter Canonica, Johann Christian Virchow, Arnaud Bourdin, Juby Jacob-Nara, Kinga Borsos, Richard H. Stanford, Zhixiao Wang, Mena Soliman, Lynn Huynh, Fariha Haque, Mei Sheng Duh, Wei-Han Cheng   +11 more
doaj   +1 more source

Eosinophilic granulomatosis with polyangiitis developed during treatment with benralizmab for severe asthma: A case report and literature review

Respirology Case Reports
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare autoimmune disorder characterized by necrotizing vasculitis, asthma, and eosinophilia. We report a case of EGPA that developed during benralizumab treatment for severe asthma and provide a ...
Mitsukuni Sakabe, Kazunori Tobino, Yumi Obata, Shota Sogabe, Kazuki Uchida, Yosuke Murakami   +5 more
doaj   +1 more source

The effects of benralizumab on lung volumes and airway resistance in severe eosinophilic asthma: a real-world study [PDF]

Introduction: Add-on biological monoclonal antibodies such as benralizumab (anti-IL-5Ra) are recommended by international guidelines to reduce exacerbations in severe eosinophilic asthma (SEA).
Alves, Carolina da Silva, Duarte-Ramos, Filipa, Gerardo, António Madeira, Gomes, Margarida, Liberato, Hedi, Lopes, Carlos, Mendes, Ana, Pardal, Cecília, Sokolova, Anna, Tonin, Fernanda   +9 more
core   +1 more source

重症好酸球性喘息におけるベンラリズマブの3次元コンピュータ断層画像解析への影響 [PDF]

新潟大学Niigata University博士（医学）Introduction: Benralizumab, an anti-interleukin-5 receptor chain monoclonal antibody, is used to treat severe asthma and control asthma symptoms or exacerbations.
Tsubokawa, Fumito, 坪川, 史人
core   +1 more source

Benralizumab Depletes IL‐5Rα‐Bearing Cells in Skin Lesions of Patients With Atopic Dermatitis

Clinical and Translational Allergy
Background Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by tissue eosinophilia and itch. We evaluated the effect of eosinophil depletion with benralizumab on markers of inflammation in the skin of patients with AD.
Christiane E. Whetstone, Ruth P. Cusack, Emma L. Price, Karen J. Howie, Caitlin Stevens, Dhuha Al‐Sajee, Suzanne Beaudin, Jennifer Wattie, Nadia Alsaji, Abbey Schlatman, Vanessa Luk, Paul M. O'Byrne, Mark D. Inman, Roma Sehmi, Hermenio Lima, Gail M. Gauvreau   +15 more
doaj   +1 more source

Benralizumab Reduces Respiratory Exacerbations and Oral Glucocorticosteroid Dose in Patients with Severe Asthma and Eosinophilic Granulomatosis with Polyangiitis

Journal of Asthma and Allergy
Carlo Mümmler,1 Pontus Mertsch,1 Michaela Barnikel,1 Frank Haubner,2 Ulf Schönermarck,3 Ulrich Grabmaier,4 Hendrik Schulze-Koops,5 Jürgen Behr,1 Nikolaus Kneidinger,1,6 Katrin Milger1 1Department of Medicine V, LMU University Hospital, LMU Munich ...
Mümmler C, Mertsch P, Barnikel M, Haubner F, Schönermarck U, Grabmaier U, Schulze-Koops H, Behr J, Kneidinger N, Milger K   +9 more
doaj  

The pediatric asthma yardstick: Practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma [PDF]

, 2018
Bacharier, Leonard B, Chipps, Bradley E, Farrar, Judith R, Jackson, Daniel J, Murphy, Kevin R, Phipatanakul, Wanda, Szefler, Stanley J, Teague, W. Gerald, Zeiger, Robert S   +8 more
core   +2 more sources

Care pathways for the selection of a biologic in severe asthma [PDF]

, 2017
Bousquet, Jean, Brusselle, Guy, Buhl, Roland, Busse, William W, Cruz, Alvaro A, Djukanovic, Ratko, Domingo, Christian, Gow, Andrew Menzies, Hanania, Nicola A, Humbert, Marc, Phipatanakul, Wanda, Wahn, Ulrich, Wechsler, Michael E   +12 more
core   +2 more sources

A case of herpes zoster following the first dose of benralizumab. [PDF]

Allergol Select
Aksu K, Telli O, Yağdıran M, Dindar Çelik F, Çelik Tuğlu H, Göktürk Ö.   +5 more
europepmc   +1 more source