Results 91 to 100 of about 13,855 (240)

Anticoccidial therapy small guide [PDF]

open access: yesMedicamentul Veterinar, 2007
Being a major challenge, because of ingenious parasite's survival strategies and treatment's transience, anticoccidal therapy it is a major priority. In this respect, therapeutic conduct must be adjusted as well is possible on the most efficient drug ...
Cristina, T. Romeo
doaj  

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

open access: yesChemistryOpen, EarlyView.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas   +4 more
wiley   +1 more source

Closed‐Loop Recyclable Polyhexahydrotriazine Aerogels Derived From PET Waste

open access: yesSmall, EarlyView.
A sustainable approach for upcycling postconsumer polyethylene terephtalate (PET) into bifunctional amine monomers, which serve as building blocks for high‐performance polyhexahydrotriazine aerogels (PHT‐As), is presented. These aerogels exhibit remarkable properties, including lightweight structure, high porosity, thermal superinsulation, and ...
Christos Pantazidis   +4 more
wiley   +1 more source

An unusual endo-selective C-H hydroarylationof norbornene by the Rh(I)-catalyzed reactionof benzamides

open access: yesNature Communications, 2017
Investigating unusual organometallic pathways may help to efficiently control product selectivity in homogeneous catalysis. Here, the authors report the hydroarylation of aromatic amides with norbornene derivatives and propose the formation of a rhodium ...
Kaname Shibata   +4 more
doaj   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

An adamantane‐based ligand as a novel chemical tool for thermosensory TRPM8 channel therapeutic modulation

open access: yesThe FEBS Journal, EarlyView.
Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti   +9 more
wiley   +1 more source

The complete absence of cytoplasmic γ‐actin results in no discernible phenotype in mice or primary fibroblasts

open access: yesThe FEBS Journal, EarlyView.
Mice and mouse embryonic fibroblasts homozygous for an Actg1 allele edited to translate β‐actin instead of γ‐actin (Actg1‐coding beta) are devoid of γ‐actin protein. We demonstrate that these Actg1c‐b/c‐b mice present with no measurable phenotype in survival, body mass, activity, muscle contractility, or auditory function.
Lauren J. Sundby   +7 more
wiley   +1 more source

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