Results 91 to 100 of about 24,787 (257)

Challenges facing the management of pesticide resistance in weeds, diseases and insect pests in European agriculture and the future of effective IPM implementation

open access: yesPest Management Science, EarlyView.
Opinion on pesticide resistance and management in the European Union (EU) and United Kingdom (UK) is presented cognisant of changes in regulation that impact on mode of action availability and cropping system choice. Abstract In recent times, pesticide resistance has been managed reasonably effectively, either proactively or reactively, by monitoring ...
Julian Smith   +10 more
wiley   +1 more source

Experimental pharmacological research regarding the antidepressant effect of associating doxepin and selegiline in normal mice [PDF]

open access: yes, 2019
The severity and complexity of depression can vary widely among individuals, thus making single drug therapy ineffective in some cases. Taking this fact into account and using a mouse model, we set on investigating the possibility of obtaining a ...
Chiriță, Cornel   +8 more
core   +2 more sources

Recent advances in fluorescent materials innovation and film‐based sensing application

open access: yesResponsive Materials, EarlyView.
This review systematically summarizes recent advances in high‐performance film‐based fluorescent sensors (FFSs), specifically covering the innovative strategies for engineering porous sensing films, and the sensitive and rapid detection for diverse target analytes. Current challenges for the further development of the sensors are discussed, guiding the
Xinyu Gou, Junxia Peng, Yu Fang
wiley   +1 more source

N,N'-1,2-Phenylenebis[4-(chloromethyl)benzamide] [PDF]

open access: yes, 2010
4 páginas, 1 esquema.-- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.N,N'-1,2-Phenylenebis[4-(chloromethyl)benzamide] (3) was obtained in 61% yield by nucleophilic acyl ...
Bachl, Jürgen, Díaz Díaz, David
core   +2 more sources

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

N-[Morpholino(phenyl)methyl]benzamide [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2009
The title compound, C(18)H(20)N(2)O(2), crystallizes with two mol-ecules in the asymmetric unit. The morpholine rings of both mol-ecules adopt chair conformations. The crystal structure is stabilized by inter-molecular N-H⋯O hydrogen bonds. One phenyl ring is disordered over two orientations in a 0.665 (5):0.335 (5) ratio.
Muruganandam, L.   +4 more
openaire   +3 more sources

Automodification of N‐terminal serine residues facilitates PARP2 release from DNA

open access: yesThe FEBS Journal, EarlyView.
PARP2 is involved in detecting DNA damage and its N‐terminal role is largely unknown. Based on biochemical and biophysical data, our findings suggest that in the presence of HPF1, N‐terminal serine 8 and 73 are enriched in auto‐ADP‐ribosylation. Our results provide insight into the mechanistic role of PARP2 N‐terminus in the PARylation‐dependent ...
Saurabh Singh Dhakar   +6 more
wiley   +1 more source

Spontaneous Transfer Of Chirality In An Atropisomerically Enriched Two-Axis System [PDF]

open access: yes, 2014
One of the most well-recognized stereogenic elements in a chiral molecule is an sp(3)-hybridized carbon atom that is connected to four different substituents.
Barrett, K. T.   +3 more
core   +3 more sources

Bifunctional organocatalysts for the asymmetric synthesis of axially chiral benzamides

open access: yesBeilstein Journal of Organic Chemistry, 2017
Bifunctional organocatalysts bearing amino and urea functional groups in a chiral molecular skeleton were applied to the enantioselective synthesis of axially chiral benzamides via aromatic electrophilic bromination.
Ryota Miyaji   +4 more
doaj   +1 more source

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