Results 71 to 80 of about 16,265 (239)
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Autolysin E (AtlE) is a cell wall degrading enzyme that catalyzes the hydrolysis of the β-1,4-glycosidic bond between the N-acetylglucosamine and N-acetylmuramic acid units of the bacterial peptidoglycan.
Jure Borišek +7 more
doaj +1 more source
Flipping the Card With Enantiodivergent Organocatalysis
Chemistry – A European Journal, EarlyView.This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre +3 more
wiley +1 more source
, 2021 Various N-(2-bromo-allyl) benzamides were used as the starting materials to study vinyl radical cyclization reactions. The vinyl radicals underwent ipso-cyclization, fragmentation, and cyclization reactions to produce β-aryl-γ-lactams with the carbonyl ...
Che-Chien Chang +5 more
core +1 more source
Exploration, EarlyView.Based on the interaction between the weakly cross‐linked disulfide bonds that break under stress and charge‐reversal messenger molecules, we herein achieved nanoparticle charge reversal under stress and constructed a stress‐responsive charge‐reversal hydrogel microsphere system using microfluidic technology.
Feng Lin +11 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.A light mediated direct regioselective B─H functionalization, via hydrogen atom transfer (HAT), is described. Unexplored xanthyl‐closo‐carboranes as novel bench‐stable and versatile platforms to access sulfur‐containing boron clusters are reported for the first time.
Marco Rusconi +9 more
wiley +2 more sources
Synthesis and Anti-inflammatory Activity of New 2,3-Dihydro-4(1H)-quinazolinone Derivatives
Zagazig Journal of Pharmaceutical Sciences, 2003 A new series of 2,3-dihydro-4(1H)-quinazolinones was synthesized by condensation of 2-methylamino-N-substituted benzamides (III) with either formaldehyde or aromatic aldehydes to produce 2,3-dihydro-1-methyl-3-(substituted phenyl)-4(1H) -quinazolinones ...
Samy Sakr
doaj +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Enantioselective Synthesis of Atropisomeric Benzamides through Peptide-Catalyzed Bromination
, 2016 We report the enantioselective synthesis of atropisomeric benzamides employing catalytic electrophilic aromatic substitution reactions involving bromination.
Scott J. Miller (1308798) +1 more
core +3 more sources
The Chemical Record, EarlyView.This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Bifunctional organocatalysts for the asymmetric synthesis of axially chiral benzamides
Beilstein Journal of Organic Chemistry, 2017 Bifunctional organocatalysts bearing amino and urea functional groups in a chiral molecular skeleton were applied to the enantioselective synthesis of axially chiral benzamides via aromatic electrophilic bromination.
Ryota Miyaji +4 more
doaj +1 more source