Results 51 to 60 of about 17,013 (236)

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Investigating Spectrum of Biological Activity of 4- and 5-Chloro-2-hydroxy-N-[2-(arylamino)-1-alkyl-2-oxoethyl]benzamides

Molecules, 2011
In this study, a series of twenty-two 5-chloro-2-hydroxy-N-[2-(arylamino)-1-alkyl-2-oxoethyl]benzamides and ten 4-chloro-2-hydroxy-N-[2-(arylamino)-1-alkyl-2-oxoethyl]benzamides is described.
Jirina Stolarikova, Jarmila Vinsova, Marcela Vejsova, Katarina Kralova, Ales Imramovsky, Matus Pesko, Josef Jampilek   +6 more
doaj   +1 more source

Synthesis of Functionalized 9-Substituted Fluorene Derivatives via Boron Trifluoride Catalysed Reaction of Coplanar 9-(Phenylethynyl)-9H-fluoren-9-ols, Aryl Aminoamides and N-Bromosuccinimide

SynOpen, 2021
A boron trifluoride catalysed reaction of coplanar 9-(phenyl­ethynyl)-9H-fluoren-9-ols with various 2-aminobenzamides affords a number of highly functionalized, conjugated (Z)-2-((2-(9H-fluoren-9-ylidene)-1-phenylethylidene)amino) benzamides in excellent
Mohanakumaran Athira, Ponnusamy Shanmugam   +1 more
doaj   +1 more source

SURMOF Induced Morphological Crystal Engineering of Substituted Benzamides

, 2018
Well-established, self-assembled monolayers are further explored and extended to SURMOFs as basic template heterosurfaces by using a basic stranded HKUST metal–organic framework (MOF) as an example.
Geetha Bolla (1744141), Geetha Bolla, Allan S. Myerson, Allan S. Myerson (1444300)   +3 more
core   +1 more source

Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents

Molecules, 2018
Three series of N-(pyrazin-2-yl)benzamides were designed as retro-amide analogues of previously published N-phenylpyrazine-2-carboxamides with in vitro antimycobacterial activity. The synthesized retro-amides were evaluated for in vitro growth inhibiting
Jan Zitko, Alžběta Mindlová, Ondřej Valášek, Ondřej Jand’ourek, Pavla Paterová, Jiří Janoušek, Klára Konečná, Martin Doležal   +7 more
doaj   +1 more source

Chromium-catalyzed para-selective formation of quaternary carbon centers by alkylation of benzamide derivatives

Nature Communications, 2018
The selective installation of quaternary carbon substituents on arenes is a highly challenging synthetic goal. Here, the authors report a chromium-catalyzed para-selective functionalization of benzamides with tertiary organometallic reagents under mild ...
Pei Liu, Changpeng Chen, Xuefeng Cong, Jinghua Tang, Xiaoming Zeng   +4 more
doaj   +1 more source

Cascade Vinyl Radical Ipso-Cyclization Reactions and the Formation of ,-Unsaturated--aryl--lactams from NPropargyl Benzamides

, 2021
Various N-(2-bromo-allyl) benzamides were used as the starting materials to study vinyl radical cyclization reactions. The vinyl radicals underwent ipso-cyclization, fragmentation, and cyclization reactions to produce β-aryl-γ-lactams with the carbonyl ...
Che-Chien Chang, Pei-Ling Wang (5866421), Pei-Ling Wang, Che-Chien Chang (283593), Chih-Hao Luo (11506449), Chih-Hao Luo   +5 more
core   +1 more source

2-(Methylsulfinyl)benzamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
In the crystal of the title compound, C(8)H(9)NO(2)S, synthesized by the oxidation of 2-(methyl-sulfan-yl)benzamide using NaOCl with 2,2,6,6-tetra-methyl-piperidyl-1-oxy (TEMPO) as the catalyst, mol-ecules are linked via inter-molecular N-H⋯O(amide) hydrogen bonds, forming centrosymmetric amide-amide dimers which are extended into a two-dimensional ...
openaire   +3 more sources

Dual‐Function Electrocatalysis: Simultaneous Wastewater Remediation and Hydrogen Evolution—A Comprehensive Review

Carbon Energy, EarlyView.
Replacing the oxygen evolution reaction with the electro‐oxidation of pollutants and waste streams offers an energy‐efficient route for simultaneous hydrogen production and pollutant remediation. This review summarizes the reaction mechanisms, catalyst design principles, and emerging paired‐electrolysis strategies that govern activity, selectivity ...
Safa Al‐Yahyaey, Rashid Al‐Hajri, Ala'a H. Al‐Muhtaseb, Hussein A. Younus, Mohammed Al‐Abri   +4 more
wiley   +1 more source

Discovery of (phenylureido)piperidinyl benzamides as prospective inhibitors of bacterial autolysin E from Staphylococcus aureus

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Autolysin E (AtlE) is a cell wall degrading enzyme that catalyzes the hydrolysis of the β-1,4-glycosidic bond between the N-acetylglucosamine and N-acetylmuramic acid units of the bacterial peptidoglycan.
Jure Borišek, Sara Pintar, Mitja Ogrizek, Simona Golič Grdadolnik, Vesna Hodnik, Dušan Turk, Andrej Perdih, Marjana Novič   +7 more
doaj   +1 more source