FeIII‐Mediated Synthesis of Azaspirodienones via Ipso‐Radical Cyclization of Ugi–4CR Adducts
An efficient two‐step protocol for the synthesis of azaspirodienones via Fe‐mediated ipso‐radical cyclization of Ugi adducts has been developed. This methodology provides rapid access to these privileged spirocyclic architectures under mild conditions, offering a practical and versatile approach to generating structurally complex molecules with ...
Silvia J. Becerra–Anaya +2 more
wiley +1 more source
A series of 4-(2-(4-substituted phenyl)-4-oxoquinazolin-3(4H)-yl)-N-(2-(4-fluorophenyl)-4-oxo-5-(arylidene)thiazolidin-3-yl) benzamides (VIa-n) have been synthesized by condensation of N-(2-(4-fluorophenyl)-4-oxothiazolidin-3-yl)-4-(4-oxo-2-(4 ...
Sukanya Nara, Achaiah Garlapati
doaj +1 more source
Telluroesters: Synthesis and Reactivity in Nucleophilic Acyl Substitution
A simple and general protocol to access telluroesters, a versatile class of organotellurium compounds serving as precursors of acyl radicals, is described. Their previously unexplored reactivity in nucleophilic acyl substitutions enables the efficient transfer of acyl moieties onto a broad range of nucleophiles under mild conditions.
Antonella Capperucci +3 more
wiley +1 more source
Cancer is one of the greatest global health challenges, with specific costs of US$25 trillion by 2050, including treatment and socioeconomic impacts. The epidermal growth factor receptor (EGFR), a central tyrosine kinase, is a key target for anticancer ...
Caroline do Nascimento Gonçalves +2 more
doaj +1 more source
Benzoxazole-benzamide hybrids: synthesis, structure-activity relationships, and multi-biological evaluation. [PDF]
Galić M +6 more
europepmc +1 more source
Ultrasonic and mechanochemical strategies for the synthesis of oxindole scaffolds mediated by hypervalent iodine(iii) reagents. [PDF]
Sivaraj N, Singh FV.
europepmc +1 more source
3d Transition Metals-Catalyzed Electrooxidative and Photoredox Asymmetric CH Activation: A Sustainable Futuristic Prospective. [PDF]
Sarthi +4 more
europepmc +1 more source
Benzamides of 2-(aminophenyl)benzimidazoles and 2-(aminophenyl)indoles as Anticancer Scaffolds: Synthesis, In Silico and In Vitro Evaluation. [PDF]
Saeed A +4 more
europepmc +1 more source
Divergent synthesis of indenoisoquinolines and indenoisochromenes by rhodium-catalysed cyclocondensation of <i>N</i>-substituted benzamides with 2-diazoindenediones. [PDF]
Kim DY, Kimura Y, Miura R, Kondo T.
europepmc +1 more source

