Results 101 to 110 of about 20,263 (222)

Structure property relationships in halogenated aromatic amides and imides [PDF]

, 2017
The effect of halogens (X) and pyridine N atom substitution patterns on molecular structure and conformation is analyzed and discussed herein. Several series of 3 x 3 isomer grids (Scheme 1; Figs 1-3) of halo-N-(pyridyl)benzamides (Xxx) (C12H9N2OX, x ...
Aubert, E., Espinosa, E., Gallagher, John F., Guillot, B., Jelsch, C., Mocilac, Pavle   +5 more
core   +2 more sources

4-Bromo-N-(diethylcarbamothioyl)benzamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
The synthesis of the title compound, C(12)H(15)BrN(2)OS, involves the reaction of 4-bromo-benzoyl chloride with potassium thio-cyanate in dry acetone, followed by condensation of 4-bromo-benzoyl isothio-cyanate with diethyl-amine. The carbonyl and thio-carbonyl bond lengths indicate that these correspond to double bonds.
Binzet, Gün, Flörke, Ulrich, Külcü, Nevzat, Arslan, Hakan   +3 more
openaire   +4 more sources

Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption

Environmental Toxicology, EarlyView.
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim, Natanael Alves da Silva, Gabriela Gomes Lima, Igor Rodrigues Vasconcelos, Luciana Souza Ondei, Elisa Flávia Luiz Cardoso Bailão, Antônio Sérgio Nakao de Aguiar, Marcelino Benvindo‐Souza, Leonardo Luiz Borges, Virgínia Damin, Luciane Madureira Almeida   +10 more
wiley   +1 more source

N-(Naphthalen-1-yl)benzamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
In the title compound, C(17)H(13)NO, the N-H and C=O bonds are anti with respect to each other. The dihedral angle between the naphthalene ring system and the phenyl ring is 86.63 (5)°. In the crystal, N-H⋯O hydrogen bonds link mol-ecules into chains along [010].
Ruitao Zhu, Yuehong Ren, Wenjuan Li
openaire   +3 more sources

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

The search for the 'next' euphoric non-fentanil novel synthetic opioids on the illicit drugs market: current status and horizon scanning [PDF]

, 2019
Purpose: A detailed review on the chemistry and pharmacology of non-fentanil novel synthetic opioid receptor agonists, particularly N-substituted benzamides and acetamides (known colloquially as U-drugs) and 4-aminocyclohexanols, developed at the Upjohn ...
A Helander, A Regina La, A Schneir, AG Hayes, AG Hayes, AJ Krotulski, AJ Krotulski, ALA Mohr, C McKenzie, C Soussan, Craig McKenzie, D Fabregat-Safont, D Lednicer, D Lednicer, D Lednicer, D Lednicer, D Lednicer, D Papsun, E Gerace, GW Peng, I Metushi, IM McIntyre, J Seither, J Szmuszkovicz, J Szmuszkovicz, JB Zawilska, JK O’Donnell, K Domanski, K Koch, KA Rambaran, Kirti Kumari Sharma, KN Ellefsen, KT Vo, L Ventura, M Dziadosz, M Katselou, MC Hout Van, MH Baumann, MJ Jones, MP Prekupec, Niamh NicDaeid, NJ Harper, P Armenian, P Armenian, P Nikolaou, PF Voigtlander Von, PF Voigtlander Von, PF Voigtlander Von, RA Fujimoto, RA Lahti, RT Brittain, SA Harding, SC Ifeagwu, SP Elliott, Tim G. Hales, TP Rohrig, USAN Council, V Coopman, Vaidya Jayathirtha Rao, W Fleming, X Ruan, Z Davey, Z Li, ZH Liu   +63 more
core   +2 more sources

Automodification of N‐terminal serine residues facilitates PARP2 release from DNA

The FEBS Journal, EarlyView.
PARP2 is involved in detecting DNA damage and its N‐terminal role is largely unknown. Based on biochemical and biophysical data, our findings suggest that in the presence of HPF1, N‐terminal serine 8 and 73 are enriched in auto‐ADP‐ribosylation. Our results provide insight into the mechanistic role of PARP2 N‐terminus in the PARylation‐dependent ...
Saurabh Singh Dhakar, Albert Galera‐Prat, Jin Cai, Julia Preisser, Tiila‐Riikka Kiema, Andreas Ladurner, Lari Lehtiö   +6 more
wiley   +1 more source

Assessment of labelled products with different radioanalytical methods: study on 18F-fluorination reaction of 4-[18F]fluoro-N-[2-[1-(2-methoxyphenyl)-1-piperazinyl]ethyl-N-2-pyridinyl-benzamide (p-[18F]MPPF) [PDF]

, 2010
Peer ...
Bergström, Kim, Koivula, Teija, Kämäräinen, Eeva-Liisa, Laine, Jaana, Lipponen, Tiina, Perhola, Outi, Solin, Olof   +6 more
core   +1 more source

Harnessing benzamides as plant stress inhibitors, growth promoters and in management of crop resilience—A review

Plant Biology, EarlyView.
Benzamides boost crop resilience by inhibiting poly(ADP‐ribose) polymerase (PARP) to enhance stress tolerance and, through their antimicrobial, herbicidal, and insecticidal derivatives, they offer broad protection for sustainable crop improvement. Abstract Benzamides have emerged as potent stress inhibitors and growth promoters in plant biotechnology ...
M. J. Koetle, T. E. Motaung, S. O. Amoo
wiley   +1 more source

Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists

Molecular Pain, 2007
Agonists of TRPA1 such as mustard oil and its key component AITC cause pain and neurogenic inflammation in humans and pain behavior in rodents. TRPA1 is activated by numerous reactive compounds making it a sensor for reactive compounds in the body ...
Immke David C, Wang Weiya, Gao BaoXi, Tamir Rami, Klionsky Lana, Nishimura Nobuko, Gavva Narender R   +6 more
doaj   +1 more source