Results 101 to 110 of about 17,013 (236)
Cancer is one of the greatest global health challenges, with specific costs of US$25 trillion by 2050, including treatment and socioeconomic impacts. The epidermal growth factor receptor (EGFR), a central tyrosine kinase, is a key target for anticancer ...
Caroline do Nascimento Gonçalves +2 more
doaj +1 more source
Substituted Benzamides Containing Azaspiro Rings as Upregulators of Apolipoprotein A-I Transcription
Apolipoprotein A-I (Apo A-I) is the principal protein component of high density lipoprotein (HDL), which is generally considered as a potential therapeutic target against atherosclerosis.
Bin Hong +7 more
doaj +1 more source
Selective Photoinduced α‐Amino C(sp3)–H Alkylation Mediated by NHC–Borane
Herein, we report a selective photoinduced functionalization of α‐amino C(sp3)─H bonds mediated by NHC–boranes. This reaction proceeds efficiently without the need for any external radical initiator or photoredox catalyst. Mechanistic studies reveal that the reaction proceeds via an efficient radical chain, featuring the formation of an aryl radical ...
Gabin Lalande +2 more
wiley +1 more source
Effect of methylated amides in the CEP profile of benzamides 48, 51 and 52.
Effect of methylated amides in the CEP profile of benzamides 48, 51 and 52.
Sonia Maria Gutiérrez Sanfeliciano (4961983) +1 more
core +1 more source
Design, anticonvulsant properties in maximal electroshock-induced seizures [MES] and seizures induced by subcutaneous administration of pentetrazole (scPtz), and neurotoxicity of retrobenzamides (N-(nitrophenyl)benzamides and N-(aminophenyl) benzamides ...
Stables, JP. +4 more
core
Anticoccidial therapy small guide [PDF]
Being a major challenge, because of ingenious parasite's survival strategies and treatment's transience, anticoccidal therapy it is a major priority. In this respect, therapeutic conduct must be adjusted as well is possible on the most efficient drug ...
Cristina, T. Romeo
doaj
Ortho-substituted arylboronic esters are efficiently coupled with carbamoyl chlorides under Pd-catalysis to give tertiary ...
Kristensen, Jesper Langgaard +3 more
core +1 more source
Pandanus odorifer methanolic extract exhibited strong antiglycation activity, moderate antioxidant capacity, and high flavonoid content. Three isolated compounds reduced Aβ‐associated ThT fluorescence, with blumenol C glucoside showing the greatest effect.
Patricia Marie P. Oliva +4 more
wiley +1 more source
Cobalt-Catalyzed Direct Carbonylation of Aminoquinoline Benzamides
A method for direct carbonylation of aminoquinoline benzamides has been developed. Reactions proceed at room temperature in trifluoroethanol solvent, use oxygen from air as an oxidant, and require Mn(OAc)3 as a cocatalyst.
Liene Grigorjeva (1332981) +1 more
core +1 more source
Heterocyclic‐Based Fungicides: Emerging Strategies for Viable Plant Disease Control
Heterocyclic compounds have attracted considerable attention because of their structural diversity, potent antifungal activity, and ability to interact with multiple fungal targets, offering broad‐spectrum protection against phytopathogens. Synthetic and semisynthetic/part‐natural scaffolds, particularly azole, quinoline, indole, cyclotryptamine, and ...
Sumit Tahlan +4 more
wiley +1 more source

