Results 101 to 110 of about 13,855 (240)
A facile synthesis and antibacterial activity of novel pyrrolo[3,4-b]quinolin-2(3H)-yl)benzamides
A new series of pyrrolo[3,4-b]quinolin-2(3H)-yl)benzamides were designed based on molecular hybridization approach and synthesized by reaction of benzohydrazide derivatives with 9-phenylfuro[3,4-b]quinoline-1,3-diones in the presence of an Et3N catalyst.
Tahere Hosseyni Largani+4 more
doaj +1 more source
Syntheses of N-[(4-Morpholinyl)alkyl]benzamides. [PDF]
Nils Löfgren+4 more
openalex +1 more source
Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari+7 more
wiley +1 more source
ABSTRACT The present research study describes the Venetoclax (VEN)‐related substances test method using RP‐HPLC/DAD techniques. It was developed and validated according to ICH Q14 and Q2(R2) guidelines. The substances were separated using an X‐Bridge Phenyl column (150 mm × 4.6 mm, 3.5 μm) and a gradient program.
Rajeshwari Dandabattina+5 more
wiley +1 more source
The production of new pyrazole amide derivatives (6a-h) and their potential against New Delhi metallo-β-lactamase-1 (NDM-1) producing bacteria was described in the present manuscript.
Gulraiz Ahmad+6 more
doaj
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
A one-pot multicomponent synthesis and application of new imidazopyridazine based N-phenylbenzamides is described. An atom-economical method involving dimethyl phthalate, substituted anilines, and pyridazine-4,5-diamine provided the desired compounds in ...
M. Shaheer Malik+12 more
doaj
In this review, the advancements in the cyclization of 1,3‐enynes to construct structurally diverse heterocyclic and carbocyclic frameworks are portrayed comprehensively. Divergent cyclization protocols along with mechanistic aspects for key transformations are also detailed. Abstract 1,3‐Enynes have demonstrated their utility as valuable precursors to
Akash P. Sakla+4 more
wiley +1 more source
Syntheses of N-Mannich Bases of Benzamide and Their Preliminary Pharmacological Testing [PDF]
Mohini Bindal, H. R. BATRA, N. S. SEKHON
openalex +1 more source
Exploration of Aromatic Hydrazides as Inhibitors of Human Carbonic Anhydrases
Hydrazide‐based derivatives were evaluated as inhibitors of human carbonic anhydrase (hCA) isoforms I, II, IV, IX, and XII. Several derivatives, particularly those with ureido‐linkers, exhibited strong inhibitory activity with inhibition constants in the low micromolar range.
German Benito Menendez+5 more
wiley +1 more source