Results 131 to 140 of about 16,265 (239)
Solid-Phase Synthesis of Tris-Benzamides as α-Helix Mimetics
, 2016 Small molecules mimicking α-helices are of great interest since numerous protein−protein interactions use helical structures at the interface. With a goal of generating libraries of α-helix mimetics, an efficient solid-phase synthetic method was ...
Jung-Mo Ahn (1863976) +1 more
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Automodification of N‐terminal serine residues facilitates PARP2 release from DNA
The FEBS Journal, Volume 293, Issue 11, Page 3274-3287, June 2026.PARP2 is involved in detecting DNA damage and its N‐terminal role is largely unknown. Based on biochemical and biophysical data, our findings suggest that in the presence of HPF1, N‐terminal serine 8 and 73 are enriched in auto‐ADP‐ribosylation. Our results provide insight into the mechanistic role of PARP2 N‐terminus in the PARylation‐dependent ...
Saurabh Singh Dhakar +6 more
wiley +1 more source
Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application
European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley +1 more source
MolbankThe title compound has been fully characterised by NMR for the first time. Fully assigned 1H and 13C NMR spectra, and the X-ray structure of two different polymorphs are presented. The polymorphs show similar molecular geometries but exhibit significantly different patterns of intermolecular interactions.
R. Alan Aitken +4 more
openaire +2 more sources
Synthesis and evaluation of novel radioiodinated benzamides for malignant melanoma
, 2014 The imaging potential of a series of [123I]benzamides was studied in mice bearing B16F0 melanoma tumors. Compound [123I]25 exhibited tumor uptake >8 %ID/g at 1 h, while that of [123I]14d and [123I]25 reached a maximum of 9−12 %ID/g at 6 h.
Greguric, I +10 more
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Synthesis and Evaluation of Novel Radioiodinated Benzamides for Malignant Melanoma
, 2016 The imaging potential of a series of [123I]benzamides was studied in mice bearing B16F0 melanoma tumors. Compound [123I]25 exhibited tumor uptake >8 %ID/g at 1 h, while that of [123I]14d and [123I]25 reached a maximum of 9−12 %ID/g at 6 h.
Xiang Liu (119470) +10 more
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The structure of benzamide [PDF]
Acta Crystallographica, 1959 C. C. F. Blake, R. W. H. Small
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, 1981 The torsional angles in 30 N-substituted benzamides and related compounds have been estimated by the use of the 13C substituent chemical shifts of the meta and para carbon atoms.
CW Fong, HG Grant
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Conformational properties of o-alkoxy-benzamides in different solvents
, 1996 Electronic absorption/emission, 1H NMR spectroscopy and quantum mechanical calculations have been used to characterize the ground-state conformation of o-methoxy-and o-hexyloxy-benzamides in different solvents.
M. Cotta Ramusino +3 more
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Ruthenium(II)-Catalyzed C–H Oxygenations of Reusable Sulfoximine Benzamides
, 2017 C–H oxygenations of synthetically meaningful sulfoximine benzamides were accomplished by a versatile ruthenium catalysis regime. The ruthenium(II) catalyst was characterized by excellent mono- and chemoselectivity as well as positional selectivity via ...
Daniel Zell (1493587) +2 more
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