Results 131 to 140 of about 20,263 (222)
ChemMedChem, Volume 21, Issue 7, 14 April 2026.A SAR study led to the identification of new 2‐phenylquinoline‐based derivatives that exhibit anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) activity by acting as ATP‐competitive inhibitors of nonstructural protein 13 (nsp13) helicase.
Giada Cernicchi +24 more
wiley +1 more source
In Silico Research in BiomedicineCancer is one of the greatest global health challenges, with specific costs of US$25 trillion by 2050, including treatment and socioeconomic impacts. The epidermal growth factor receptor (EGFR), a central tyrosine kinase, is a key target for anticancer ...
Caroline do Nascimento Gonçalves +2 more
doaj +1 more source
Anticoccidial therapy small guide [PDF]
Medicamentul Veterinar, 2007 Being a major challenge, because of ingenious parasite's survival strategies and treatment's transience, anticoccidal therapy it is a major priority. In this respect, therapeutic conduct must be adjusted as well is possible on the most efficient drug ...
Cristina, T. Romeo
doaj
AntibioticsBackground/Objectives: The bacterial cell division machinery is emerging as an attractive target for antimicrobial compounds. FtsZ, a highly conserved essential division protein, is the target for a number of small molecules such as benzamides.
Lorenzo Suigo +3 more
doaj +1 more source
Nature Communications, 2017 Investigating unusual organometallic pathways may help to efficiently control product selectivity in homogeneous catalysis. Here, the authors report the hydroarylation of aromatic amides with norbornene derivatives and propose the formation of a rhodium ...
Kaname Shibata +4 more
doaj +1 more source
High performance mixed bisimide resins and composites based thereon [PDF]
, 1986 Mixtures of bismaleimide/biscitraconirnide resins produces materials which have better handling, processing or mechanical and thermal properties, particularly in graphite composites, than materials made with the individual resins. The mechanical strength
ations., Parker, J. A.
core +1 more source
Palladium-Catalyzed Oxidation of β-C(sp3)-H Bonds of Primary Alkylamines through a Rare Four-Membered Palladacycle Intermediate. [PDF]
, 2020 Site-selective functionalizations of C-H bonds are often achieved with a directing group that leads to five- or six-membered metallacyclic intermediates. Analogous reactions that occur through four-membered metallacycles are rare. We report a challenging
Bunescu, Ala +5 more
core +1 more source
Antiallergic Activity of Substituted Benzamides: Characterization, Estimation and Prediction [PDF]
, 2007 Antiallergic activity of twenty-three substituted N 4-methoxyphenyl benzamides was model by the use of an original methodology. After sketching out the compounds structure and creating the file with the observed activities, strictly based on compounds ...
BOLBOACA, Dr. Sorana D. +1 more
core
Determination of Hammett Pyridine 3-Aza and 4-Aza Replacement Constants by 1H NMR Studies of Amide Systems [PDF]
, 1993 Values for Hammett pyridine 3-aza and 4-aza replacement constants were obtained by correlation of the amide proton chemical shifts (in DMSO) of some N-(3-pyridyl)-and N-(4-pyridyl)-dichloronicotinamides, benzamides and acetamides with those of their N ...
Setliff, Frank L. +2 more
core +1 more source
Nature CommunicationsHydrazides, N-N containing structural motifs, are important due to their presence in a wide variety of biologically significant compounds. While the homo N-N coupling of two NH moieties to form the hydrazide N-N bond is well developed, the cross ...
Subban Kathiravan +3 more
doaj +1 more source