Experimental pharmacological research regarding some newly synthesized benzamides on central nervous system functions [PDF]
Journal of Mind and Medical Sciences, 2017 Three newly synthesized benzamides by the Department of Pharmaceutical Chemistry of the Faculty of pharmacy from the University of Medicine and Pharmacy „Carol Davila” Bucharest were tested in order to determine whether these new molecules have similar ...
Cornel Chiriță +4 more
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Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750 [PDF]
, 2004 Azaadamantanone 1 was converted to a series of aminoazaadamantane benzamides 9a–d, which were profiled for serotonin receptor activity. Aminomethylazaadamantane SC-54750 is a potent 5-HT4 agonist and 5-HT3 antagonist with in vivo efficacy in ...
Daniel P. Becker +3 more
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Photoredox-catalyzed arylation of isonitriles by diaryliodonium salts towards benzamides [PDF]
Beilstein Journal of Organic ChemistryThe arylation of isonitriles by diaryliodonium salts under photoredox conditions has been proposed for the first time. The suggested procedure allows preparing a broad range of benzamides using both symmetric and unsymmetric diaryliodonium salts under ...
Nadezhda M. Metalnikova +6 more
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Effectiveness of anti-psychotics and related drugs in the Huntington French-speaking group cohort. [PDF]
PLoS ONE, 2014 PURPOSE: Huntington's disease is a rare condition. Patients are commonly treated with antipsychotics and tetrabenazine. The evidence of their effect on disease progression is limited and no comparative study between these drugs has been conducted.
Gaëlle Désaméricq +17 more
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Antiviral Mechanisms of N-Phenyl Benzamides on Coxsackie Virus A9 [PDF]
Pharmaceutics, 2023 Enteroviruses are one of the most abundant groups of viruses infecting humans, and yet there are no approved antivirals against them. To find effective antiviral compounds against enterovirus B group viruses, an in-house chemical library was screened ...
Mira Laajala +7 more
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Iodide/Nickel Co-Catalyzed Manganese-Mediated Denitrogenative Cross-Electrophile Coupling of Benzotriazinones with Alkyl Sulfonates [PDF]
MoleculesAn efficient Ni-catalyzed, Mn-mediated denitrogenative cross-electrophile coupling of N-alkyl-1,2,3-benzotriazinones with alkyl tosylates and mesylates for access to o-alkyl secondary benzamides is reported.
Yingying Hong, Xuanxuan Zhang, Gang Zou
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Management of Clozapine Induced Hypersalivation on Slow Stream Rehabilitation Ward [PDF]
BJPsych OpenAims: Sialorrhoea (hypersalivation), a common side effect of clozapine can impact the quality of life of patients. At present, no drugs are licensed to manage clozapine-induced hypersalivation, but there are various practical and pharmacological ...
Neeti Sud, Yousra Ghandour
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Studies of the Synthesis of Fused Isoxazoline/Isoquinolinones and Evaluation of the Antifungal Activity of Isoxazole-like Benzamide and Isoquinolinone Hybrids [PDF]
MoleculesIsoxazole derivatives (isoxazoles, isoxazolines, and isoxazolidines) are present in the structure of several natural products and/or pharmaceutically interesting compounds.
Konstantinos A. Ouzounthanasis +3 more
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QSAR study of benzylidene hydrazine benzamides derivatives with in vitro anticancer activity against human lung cancer cell line A459 [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2023 Context: In the last decade, resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in lung cancer cases has been widespread. The discovery and development of new drugs need to be done to overcome the case.
Galih Satrio Putra +6 more
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Molecules, 2021 A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl ...
Guoxiong Hua +4 more
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