Results 11 to 20 of about 20,263 (222)

Experimental pharmacological research regarding some newly synthesized benzamides on central nervous system functions [PDF]

Journal of Mind and Medical Sciences, 2017
Three newly synthesized benzamides by the Department of Pharmaceutical Chemistry of the Faculty of pharmacy from the University of Medicine and Pharmacy „Carol Davila” Bucharest were tested in order to determine whether these new molecules have similar ...
Cornel Chiriță, Emil Ștefănescu, Cristina D. Marineci, Simona Negreș, Diana C. Nuță   +4 more
doaj   +5 more sources

Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins

Molecules, 2019
A mild rhodium-catalyzed annulation of Boc-protected benzamides with diazo compounds via C−C/C−O bond formation has been explored. In the presence of [Cp*RhCl2]2, AgSbF6 and Cs2CO3, Boc-protected benzamides can be effectively annulated to ...
Guangyu Dong, Chunpu Li, Hong Liu
exaly   +3 more sources

Photoredox-catalyzed arylation of isonitriles by diaryliodonium salts towards benzamides [PDF]

Beilstein Journal of Organic Chemistry
The arylation of isonitriles by diaryliodonium salts under photoredox conditions has been proposed for the first time. The suggested procedure allows preparing a broad range of benzamides using both symmetric and unsymmetric diaryliodonium salts under ...
Nadezhda M. Metalnikova, Nikita S. Antonkin, Tuan K. Nguyen, Natalia S. Soldatova, Alexander V. Nyuchev, Mikhail A. Kinzhalov, Pavel S. Postnikov   +6 more
doaj   +2 more sources

Effectiveness of anti-psychotics and related drugs in the Huntington French-speaking group cohort. [PDF]

PLoS ONE, 2014
PURPOSE: Huntington's disease is a rare condition. Patients are commonly treated with antipsychotics and tetrabenazine. The evidence of their effect on disease progression is limited and no comparative study between these drugs has been conducted.
Gaëlle Désaméricq, Guillaume Dolbeau, Christophe Verny, Perrine Charles, Alexandra Durr, Katia Youssov, Clémence Simonin, Jean-Philippe Azulay, Christine Tranchant, Cyril Goizet, Philippe Damier, Emmanuel Broussolle, Jean-François Demonet, Graca Morgado, Laurent Cleret de Langavant, Isabelle Macquin-Mavier, Anne-Catherine Bachoud-Lévi, Patrick Maison   +17 more
doaj   +5 more sources

Management of Clozapine Induced Hypersalivation on Slow Stream Rehabilitation Ward [PDF]

BJPsych Open
Aims: Sialorrhoea (hypersalivation), a common side effect of clozapine can impact the quality of life of patients. At present, no drugs are licensed to manage clozapine-induced hypersalivation, but there are various practical and pharmacological ...
Neeti Sud, Yousra Ghandour
doaj   +2 more sources

Iodide/Nickel Co-Catalyzed Manganese-Mediated Denitrogenative Cross-Electrophile Coupling of Benzotriazinones with Alkyl Sulfonates [PDF]

Molecules
An efficient Ni-catalyzed, Mn-mediated denitrogenative cross-electrophile coupling of N-alkyl-1,2,3-benzotriazinones with alkyl tosylates and mesylates for access to o-alkyl secondary benzamides is reported.
Yingying Hong, Xuanxuan Zhang, Gang Zou
doaj   +2 more sources

QSAR study of benzylidene hydrazine benzamides derivatives with in vitro anticancer activity against human lung cancer cell line A459 [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2023
Context: In the last decade, resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in lung cancer cases has been widespread. The discovery and development of new drugs need to be done to overcome the case.
Galih Satrio Putra, Melanny Ika Sulistyowaty, Tegar Achsendo Yuniarta, Yahmin Yahmin, Sumari Sumari, Charinrat Saechan, Takayasu Yamauchi   +6 more
doaj   +1 more source

Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives

Molecules, 2021
A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl ...
Guoxiong Hua, Cameron L. Carpenter-Warren, David B. Cordes, Alexandra M. Z. Slawin, J. Derek Woollins   +4 more
doaj   +1 more source

Base-Promoted One-Pot Synthesis of Pyridine Derivatives via Aromatic Alkyne Annulation Using Benzamides as Nitrogen Source

Molecules, 2021
In the presence of Cs2CO3, the first simple, efficient, and one-pot procedure for the synthesis of 3,5-diaryl pyridines via a variety of aromatic terminal alkynes with benzamides as the nitrogen source in sulfolane is described. The formation of pyridine
Hina Mehmood, Muhammad Asif Iqbal, Muhammad Naeem Ashiq, Ruimao Hua   +3 more
doaj   +1 more source

Structure-Based Bioisosterism Design, Synthesis, Biological Evaluation and In Silico Studies of Benzamide Analogs as Potential Anthelmintics

Molecules, 2022
A recent screen of 67,012 compounds identified a new family of compounds with excellent nematicidal activity: the ortho-substituted benzamide families Wact-11 and Wact-12.
Franco Vairoletti, Margot Paulino, Graciela Mahler, Gustavo Salinas, Cecilia Saiz   +4 more
doaj   +1 more source