Results 121 to 130 of about 37,139 (276)

The TOP‐GERD Trial: Comparative Efficacy of Tegoprazan Versus Pantoprazole in the Treatment of Erosive Oesophagitis in a Non‐Asian Population

Alimentary Pharmacology &Therapeutics, EarlyView.
In this randomized, double‐blind trial in Mexican adults with erosive oesophagitis, tegoprazan did not significantly improve the primary 4‐week ITT healing endpoint versus pantoprazole (88.9% vs. 79.4%; p = 0.33), but produced faster symptom improvement. Encouraging per‐protocol and severe‐oesophagitis findings warrant confirmation.
José M. Remes‐Troche, Luis Raúl Valdovinos‐García, C. Prakash Gyawali, José Luis Vargas‐Basurto, Carlos Alberto Reyes‐Medina, Gisselle Vanessa González‐Hernández, A. Rafael Bernal Mendez, H. H. Barragán Cordova, Pablo Thomas‐Dupont, Peter Grube‐Pagola   +9 more
wiley   +1 more source

Structures of congocidine congeners and tris-benzimidazole.

, 2019
Structures of congocidine congeners and tris-benzimidazole.
Peris Amwayi (237894), Mark Wamalwa (679106), Dickson Kinyanyi (7321574), George Obiero (7321577)   +3 more
core   +1 more source

Anthelmintic resistance in sheep nematodes in Australia: a compilation of recent test results

Australian Veterinary Journal, EarlyView.
Objective The results of recent faecal egg count reduction tests (FECRTs) were collated to provide an indication of the prevalence and severity of anthelmintic resistance in sheep nematodes across Australia and of changes in comparison to earlier testing reports.
RB Besier, NM Rolls
wiley   +1 more source

Antiproliferative effect of silver compounds containing benzimidazole ring

Trakya University Journal of Natural Sciences
With its significant biological activities, the benzimidazole nucleus is a crucial pharmacophore in medicine. Recent studies have focused on the synthesis and biological activity of benzimidazole compounds.
Senem Akkoç, Buket Banu Özkan, Dilek Bahar   +2 more
doaj   +1 more source

Pharmacological evaluation of benzimidazole derivatives with potential antiviral and antitumor activity

, 2012
In recent years the synthesis of benzimidazole and its derivatives has attracted the attention of many organic chemists because of the compounds' interesting biological activity and the crucial importance of the benzimidazole unit in the function of ...
Abu-Bakr, Sherifa M., Bassyouni, Fatma A., Rehim, Mohamed Abdel,   +2 more
core   +1 more source

Natural product‐derived TRPM7 channel inhibitors in neurological injury: Mechanisms, pharmacological potential and translational challenges

British Journal of Pharmacology, EarlyView.
Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang, Hio Lam Ho, F. David Horgen, Andrea Fleig, Zhong‐Ping Feng, Hong‐Shuo Sun   +5 more
wiley   +1 more source

Antiproliferative and Pro-Apoptotic Activity and Tubulin Dynamics Modulation of 1H-Benzimidazol-2-yl Hydrazones in Human Breast Cancer Cell Line MDA-MB-231

Molecules
(1) Background: The aim of the work is the evaluation of in vitro antiproliferative and pro-apoptotic activity of four benzimidazole derivatives containing colchicine-like and catechol-like moieties with methyl group substitution in the benzimidazole ...
Denitsa Yancheva, Maria Argirova, Irina Georgieva, Vanya Milanova, Maya Guncheva, Miroslav Rangelov, Nadezhda Todorova, Rumiana Tzoneva   +7 more
doaj   +1 more source

Characterization of benzimidazole-resistant strains of rhynchosporium-secalis

, 1994
Benzimidazole-resistant mutants of Rhynchosporium secalis were easily generated in the laboratory using UV mutagenesis. Three levels of resistance were identified (low, LR; moderate, MR; high, HR), but there was no negative cross-resistance with N ...
Hollomon, D. W., Sheila Kendall, Ishii, H., Steven P. Heaney, Kendall, S., Hideo Ishii, Derek W. Hollomon, Heaney, S. P., Hollomon, Derek W.   +8 more
core   +1 more source

Sustainable control of cyathostomin infections in practice

Equine Veterinary Education, EarlyView.
Summary Cyathostomins are the most prevalent helminths in horses and are found in nearly all grazing groups. These parasites have been shown to exhibit widespread anthelmintic resistance and can cause clinical disease, so they are a growing concern.
J. B. Matthews, T. S. Mair
wiley   +1 more source

Processable, high T-g polyimides from unsymmetrical diamines containing 4-phenoxy aniline and benzimidazole moieties

, 2018
Two novel unsymmetric diamine isomers, 6-amino-2-(4-(4-aminophenoxy)phenyl)-1H-benzimidazole (3p) and 6-amino-2-(3-(4-aminophenoxy)phenyl)-1H-benzimidazole (3 m), were synthesized and employed to react with several aromatic dianhydrides to yield two new ...
Sidra, Lala Rukh, Mushtaq, Nafeesa, Ma, Kai, Chen, Guofei, Li, Cuiyun, Fang, Xingzhong   +5 more
core