Results 11 to 20 of about 33,790 (273)
Антибиотики и Химиотерапия, 2023 Background. Antibiotic resistance of bacteria is a serious concern for modern medicine. The search for new compounds with a pronounced antibacterial effect is an urgent task of pharmaceutical chemistry.
R. S. Begunov +4 more
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Dual Photochemistry of Benzimidazole
The Journal of Organic Chemistry, 2023 Monomers of benzimidazole trapped in an argon matrix at 15 K were characterized by vibrational spectroscopy and identified as 1H-tautomers exclusively. The photochemistry of matrix-isolated 1H-benzimidazole was induced by excitations with a frequency-tunable narrowband UV light and followed spectroscopically.
José P. L. Roque +3 more
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New Perspectives in Therapy of Intoxications by Organophosphoric Compounds
Eurasian Chemico-Technological Journal, 2003 Little references actually exist on neutralization therapy which could constitute the missing ring from an efficient treatment. As structural model capable to interact with organophosphoric substances, at the level of phosphor (P) atom, the common ...
V. Sunel +3 more
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Frontiers in Pharmacology, 2021 Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole scaffolds are considerably prevalent.
Shejuti Rahman Brishty +5 more
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Journal of Advanced Research, 2017 The aim of this present study was to synthesize 2-substituted and 1,2-disubstituted benzimidazole derivatives to investigate their antibacterial diversity for possible future drug design.
Olayinka O. Ajani +4 more
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Coumarin – benzimidazole hybrids: A review on diverse synthetic strategies
Results in Chemistry, 2022 Benzimidazole and coumarin are highly significant pharmacophores in medicinal chemistry due to their numerous and compelling biological activities. It has been found that combining two or more pharmacophores in a single moiety can improve the efficiency ...
C.G. Arya +6 more
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Benzimidazoles: A biologically active compounds
Arabian Journal of Chemistry, 2017 Synthesis of commercially available benzimidazole involves condensation of o-phenylenediamine with formic acid. The most prominent benzimidazole compound in nature is N-riosyldimethylbenzimidazole, which serves as a axial ligand for cobalt in vitamin B12.
Salahuddin +2 more
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Proton‐conducting polymers based on benzimidazoles and sulfonated benzimidazoles
Journal of Polymer Science Part A: Polymer Chemistry, 2002 AbstractA sulfonated derivative of polybenzimidazole is reported, and its properties are analyzed in comparison with related polybenzimidazole proton‐conducting materials. Poly(2,5‐benzimidazole), poly(m‐phenylenebenzobisimidazole), and poly[m‐(5‐sulfo)‐phenylenebenzobisimidazole] were prepared by condensation of the corresponding monomers in ...
Juan Antonio Asensio +2 more
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Benzimidazole and its derivatives: Recent Advances (2020–2022)
Results in Chemistry, 2023 Benzimidazoles are fused heterocyclic ring systems containing two nitrogen atoms. They have vital therapeutic significance in drug discovery. Many clinically approved drugs have been developed from benzimidazole, and these include liarozole and ...
Oluwakemi Ebenezer +3 more
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Results in Chemistry, 2023 Heterocyclic compounds are foundational in drug discovery, constituting the core structure of approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical aromatic heterocyclic system present in natural compounds, playing an ...
Neha D. Mahurkar +4 more
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