Results 81 to 90 of about 35,659 (254)

Cyclic Benzimidazole Derivatives and Their Antitumor Activity [PDF]

Kemija u Industriji, 2008
Over the past years benzimidazole derivatives are one of the most extensively studied classes of heterocyclic compounds, and have received much attention from synthetic organic as well as medicinal chemists, because of their well known biological ...
Karminski-Zamola, G., Hranjec, M.
doaj  

Synthesis and biological evaluation of radio-iodinated benzimidazoles as SPECT imaging agents for NR2B subtype of NMDA receptor. [PDF]

, 2010
In this study, the benzimidazole derivatives were synthesized and evaluated as imaging agents for the NR2B subtype of NMDA receptor. Among these ligands, 2-{[4-(4-iodobenzyl)piperidin-1-yl]methyl}benzimidazol-5-ol (8) and N-{2-[4-(4-iodobenzyl)-piperidin-
Mamoru Haratake, Ogawa, Mikako, Yasuhiro Magata, Le Biao, Nakayama, Morio, Haratake, Mamoru, Magata, Yasuhiro, Takeshi Fuchigami, Fuchigami, Takeshi, Biao, Le, Yamaguchi, Hiroshi, Hiroshi Yamaguchi, Mikako Ogawa, Morio Nakayama   +13 more
core   +1 more source

Detection of Nitazenes in the Illicit Drug Supply Utilizing Precursor Ion Scan Methods With Paper Spray Mass Spectrometry

Drug Testing and Analysis, EarlyView.
Nitazenes are increasingly present in the illicit drug supply, complicating harm reduction efforts. We have developed a rapid, nontargeted precursor ion scan method to detect emerging nitazenes in real‐world opioid samples. The method identified multiple nitazenes, often replacing pharmaceutical opioids or mixed with fentanyl and benzodiazepines ...
Allie Miskulin, Irene Shkolnikov, Jindar Sboto, Collin Kielty, Bruce Wallace, Chris G. Gill, Dennis K. Hore   +6 more
wiley   +1 more source

Using allele-specific oligonucleotide probes to characterize benzimidazole resistance in Rhynchosporium secalis

, 1995
Benzimidazole fungicides are important mixture components in strategies to combat fungicide resistance in Rhynchosporium secalis Davis. To monitor the performance of these strategies, a rapid, accurate assay has been developed to detect point mutations ...
Hollomon, D. W., Butters, J., Wheeler, J. E., Kendall, S. J., Hall, L.   +4 more
core  

Synergistic‐Induced Perovskite Phase Distribution and Lattice Stabilization for Efficient and Stable Sky‐Blue PeLEDs

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
We have developed a multifunctional buried‐interface engineering strategy using phenethylammonium thiocyanate to regulate quasi‐2D perovskite crystallization and stabilize the lattice. The synergistic effects of SCN− and PEA+ steric confinement promote phase redistribution toward n = 2, suppressing interfacial defects and enabling the production of ...
He Dong, Xiao Qin, Hongyan Chen, Mingrui Lv, Xin Wang, Zhuolin Zhan, Jie Hua, Yuan Chai, Mimi Sun, Jianan Dai, Haipeng Jiang, Jin Wang   +11 more
wiley   +1 more source

Benzimidazole derivatives as kinase inhibitors

, 2014
Benzimidazole is a common kinase inhibitor scaffold and benzimidazole-based compounds interact with enzymes by multiple binding modes. In some cases, the benzimidazole acts as part of the hinge-binding motif, in others it has a scaffolding role without ...
Garuti L, Roberti M, Bottegoni, Giovanni, Roberti, Marinella, Bottegoni G., Garuti, Laura   +5 more
core   +1 more source

Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective

Equine Veterinary Journal, EarlyView.
Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén, I. R. Hellings, K. Toft Nielsen, A. Bergren, I. Holmgren, S. Attin, T. Pihl, A. Kendall, Y. Hedberg Alm   +8 more
wiley   +1 more source

A review on synthetic routes and pharmacological applications of thiophene clubbed benzimidazoles

Discover Chemistry
The heterocyclic moiety benzimidazole holds significant importance as a primary “biolinker” in various synthetic strategies employed for the development of bioactive compounds.
Binitha Sreedharan Daisylet, Selwin Joseyphus Raphael, C. Justin Dhanaraj, Arish Dasan   +3 more
doaj   +1 more source

Bis(1-benzyl-1H-benzimidazole-κN3)dichloridozinc

Acta Crystallographica Section E, 2014
In the title compound, [ZnCl2(C14H12N2)2], the ZnII atom exhibits a distorted tetrahedral coordination geometry involving two chloride anions and two N-atom donors from 1-benzyl-1H-benzimidazole ligands.
Rachid Bouhfid, El Mokhtar Essassi, Mohamed Saadi, Lahcen El Ammari   +3 more
doaj   +1 more source

Highly efficient blue crystalline organic light‐emitting diodes enabled by a hot exciton sensitizer PyPO

FlexMat, EarlyView.
Two different sensitization structures (hot exciton sensitizer type and exciton nanoaggregate type) were integrated into crystalline host matrix. The resulting crystalline organic light‐emitting diodes exhibit low Joule heat loss ratio and high photon output.
Hao Hu, Bo Yu, Ping Lu, Feng Zhu, Donghang Yan   +4 more
wiley   +1 more source