Results 11 to 20 of about 9,350 (208)

Evaluation of the effects of some benzimidazole derivatives on germination parameters of wheat varieties [PDF]

Journal of Agricultural Sciences (Belgrade)
This study aims to investigate the effect of some benzimidazole derivatives on the germination parameters of bread and durum wheat varieties. These derivatives contain both unsubstituted and substituted benzimidazole structures to determine the effect of
Külen Seda, Dincer Sebla
doaj   +1 more source

Benzimidazole scaffolds as promising antiproliferative agents: a review

BMC Chemistry, 2019
Cancer is one of the most serious medical problem and second leading cause of death in the world, characterized by a deregulation of the cell cycle which mainly results in a progressive loss of cellular differentiation and uncontrolled cellular growth ...
Sumit Tahlan, Sanjiv Kumar, Saloni Kakkar, Balasubramanian Narasimhan   +3 more
doaj   +1 more source

Aminoacids Derivatives with a Potential Anti-inflammatory Activity

Eurasian Chemico-Technological Journal, 2003
The paper presents the synthesis of benzimidazole derivatives starting from asparagic acid. The reaction products were analysed from physical and chemical point of view and their biological activity (acute toxicity, anti-inflammatory activity and ...
V. Sunel, M. Popa, L. Verestiuc, C. Ivanov, A. A. Popa   +4 more
doaj   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

The Benzimidazole Derivatives, B1 (N-[(1H-Benzimidazol-2-yl)Methyl]-4-Methoxyaniline) and B8 (N-{4-[(1H-Benzimidazol-2-yl)Methoxy]Phenyl}Acetamide) Attenuate Morphine-Induced Paradoxical Pain in Mice

Frontiers in Neuroscience, 2019
Despite being routinely used for pain management, opioid use is limited due to adverse effects such as development of tolerance and paradoxical pain, including thermal hyperalgesia and mechanical allodynia.
Zahida Idris, Muzaffar Abbas, Humaira Nadeem, Arif-ullah Khan   +3 more
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Revealing analgesic and anxiolytic potentials of synthetic benzimidazole analogues: An in-vivo and in-silico study

Pakistan Journal of Pharmaceutical Sciences, 2023
Certain drugs have potential to affect and alter individual’s behavior. On the other hand, pain is a complex phenomenon with various treatment options; analgesic medicines are the primary source.
Shamim Akhtar, Sabahat Naeem, Nadia Asghar, Faisal Muhammad Khan, Moona Mehboob Khan, Arfa Akram, Imran Suheryani Karachi, Pakistan   +7 more
doaj   +1 more source

Synthesis and Characterization of Novel Pyrimido [1,2-a] benzimidazole and its Derivatives

Al-Mustansiriyah Journal of Science, 2022
A few pyrimido[1,2-a] benzimidazole derivatives had been synthesized, derived from 4-amino-2-(4-chloro or bromophenyl) -1,2-dihydropyrimido[1,2-a] benzimidazole-3-carbonitrile (4 or 5) is made through one pot three components condensation reaction of 1H ...
Fadhel R. Hafedh, Hamid H. Mohammed, Zainab N. Mageed   +2 more
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Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

Angewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources

Relationship between intraocular pressure lowering effect and chemical structure of imidazo[1,2-a]benzimidazole and pyrimido[1,2-a]benzimidazole derivatives

Data in Brief, 2018
This article contains data that relate to the study carried out in the work of Marcus et al. (2018) [1]. Data represent an information about pharmacophore analysis of imidazo[1,2-a]benzimidazole and pyrimido[1,2-a]benzimidazole derivatives and results of
Pavel Vassiliev, Igor Iezhitsa, Renu Agarwal, Adrian Julian Marcus, Alexander Spasov, Olga Zhukovskaya, Vera Anisimova   +6 more
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A Mild Disilane‐Enabled Halide‐to‐Deuterium Manifold With D2O for Aryl and Benzylic Halides

Angewandte Chemie, EarlyView.
A broadly applicable Pd‐catalyzed dehalogenative deuteration enables efficient conversion of aryl and benzylic halides with inexpensive deuterium oxide (D2O). The method proceeds under exceptionally mild conditions without strong bases, harsh reductants, or stoichiometric Lewis acid halide scavengers, and tolerates a wide range of functional groups ...
Wenliang Wang, Ryan Parlett, Liam Hornstein, Landon Conklin, Qi Tang, Xiaodong Shi   +5 more
wiley   +2 more sources