Results 41 to 50 of about 636,119 (261)

Synthesis and Characterization of Novel Benzimidazole Derivatives using CdO NPs and their Application as Antibacterial and Antifungal Agents

Al-Mustansiriyah Journal of Science
Background: Benzimidazoles are a class of compounds characterized by a fusion of benzene and imidazole rings. This unique structure endows them with a broad spectrum of biological activities, making them invaluable in medicinal and pharmaceutical ...
Asmaa M. Abdullah, Abdull Jabar Kh. Attia, Sergei N. Shtykov   +2 more
doaj   +1 more source

Antimicrobial potential of 1H-benzo[d]imidazole scaffold: a review

BMC Chemistry, 2019
Background Benzimidazole is a heterocyclic moiety whose derivatives are present in many of the bioactive compounds and posses diverse biological and clinical applications.
Sumit Tahlan, Sanjiv Kumar, Balasubramanian Narasimhan   +2 more
doaj   +1 more source

Modular Access to α‐Tertiary Amines: Electrochemical Tandem Di‐Functionalization of Olefins With Ammonia Surrogates and Amino Acids

Angewandte Chemie, EarlyView.
A metal‐ and oxidant‐free electrochemical multicomponent di‐functionalization strategy that rapidly converts 1,1‐disubstituted alkenes into α‐tertiary primary amines with simultaneous installation of bio‐relevant sulfur or selenium motifs was devised for late‐stage functionalization. ABSTRACT Quaternary carbon centers, especially those bearing nitrogen,
Adrija Ghosh, Tarun, Sven Erik Peters, Lutz Ackermann, Debasis Banerjee   +4 more
wiley   +2 more sources

Characterisation of the benzimidazole-binding site on the cytoskeletal protein tubulin [PDF]

, 2003
The binding kinetics of several benzimidazole compounds were determined with recombinant tubulin monomers and heterodimers from benzimidazole-sensitive and -insensitive organisms.
MacDonald, Louisa M.
core  

PART I: MICROWAVE-ASSISTED SYNTHESIS OF BENZIMIDAZOLES: AN OVERVIEW (UNTIL 2013)

Journal of the Turkish Chemical Society, Section A: Chemistry, 2016
Benzimidazole derivatives are interesting heterocycles and are found in many naturally occurring products and various drugs. They exhibit several  pharmacological activities such as antitumor, diuretic, fungicidal, bactericidal, antihelmintic ...
Hasan Küçükbay
doaj   +1 more source

Decoding Synergistic Pathways in Bimetallic MOFs for Advanced Oxidation Processes

Advanced Materials, EarlyView.
This review presents a unified framework linking metal pairing and framework design with electronic structure, redox cycling, oxidant activation, reactive‐species generation, and catalytic performance across photocatalytic and oxidant‐based BMOF‐AOPs. The resulting design principles guide the development of hydrolytically stable and efficient BMOFs for
Karim El‐Naggar, Huayang Zhang, Shaobin Wang   +2 more
wiley   +1 more source

Synthesis and biological evaluation of 2-substituted benzimidazole derivatives [PDF]

, 2015
A novel series of 2-substituted benzimidazole derivatives (3a–3j) were synthesized by the reaction of 2-chloro methyl benzimidazole with substituted primary aromatic amines.
Patangia, Uddhav, Faruk Alam, Nath, Shyamalendu, Hazarika, Rajib, Alam, Faruk, Gurusamy Mariappan, Mariappan, Gurusamy, Rajib Hazarika, Uddhav Patangia, Rashmi Karki, Karki, Rashmi, Shyamalendu Nath   +11 more
core   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

Advanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang, Narina Jung, Min‐Hyeok Kim, Wanyoung Lim, Zhenzhong Chen, Byung Mook Weon, Sungsu Park   +6 more
wiley   +1 more source

Sensitivity of Haemonchus contortus to anthelmintics using different in vitro screening assays: a comparative study

Parasites & Vectors, 2022
Background Helminthiasis and resistance to commercial anthelmintic compounds are major causes of economic losses for livestock producers, resulting in an urgent need for new drugs and reliable in vitro screening tests capable of detecting potentially ...
Beatriz Munguía, Jenny Saldaña, Magdalena Nieves, María Elisa Melian, Manuela Ferrer, Ramiro Teixeira, Williams Porcal, Eduardo Manta, Laura Domínguez   +8 more
doaj   +1 more source

Accelerating Discovery of Organic Molecular Crystals via Materials Informatics and Autonomous Experiments

Advanced Intelligent Discovery, EarlyView.
Materials informatics and autonomous experimentation are transforming the discovery of organic molecular crystals. This review presents an integrated molecule–crystal–function–optimization workflow combining machine learning, crystal structure prediction, and Bayesian optimization with robotic platforms.
Takuya Taniguchi, Kazuki Ishizaki, Ryo Fukasawa   +2 more
wiley   +1 more source