Results 51 to 60 of about 9,350 (208)

Green synthetic approaches to benzimidazole scaffolds: recent advances in antimicrobial and anticancer drug discovery

open access: yesResults in Chemistry
The growing demand for sustainable and efficient drug development has directed significant attention toward green chemistry in heterocyclic synthesis. Among various pharmacophores, benzimidazole has emerged as a privileged scaffold due to its remarkable ...
Mrityunjay Banerjee   +7 more
doaj   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon   +3 more
wiley   +1 more source

Microwave-assisted synthesis of some nitro-benzimidazoles and their salicyl and isatin Schiff bases

open access: yesBulletin of the Chemical Society of Ethiopia, 2017
A series of 5-nitrosubstituted benzimidazole and 6-nitro substituted benzimidazole derivatives were synthesized starting from iminoester hydrochloride and 4-nitro-o-phenylenediamine under microwave irradiation.
F. Yılmaz, N. Karaali, S. Şaşmaz
doaj   +1 more source

Recent Advances in Ionizing Radiation as a Nonequilibrium Chemical Field for Catalysis

open access: yesCarbon and Hydrogen, EarlyView.
Ionizing radiation acts as a nonequilibrium chemical field that generates reactive species and structural perturbations. These radiation‐induced effects bridge catalytic material construction, including metal loading, framework evolution, defect engineering, and carbon‐network reorganization, with selective transformations such as oxidation, reduction,
Junhua Kuang   +8 more
wiley   +1 more source

Skin Damages—Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System

open access: yesMolecules, 2020
In the search for scaffolds for multifunctional compounds we investigated the structure activity relationship of a class of benzimidazole derivatives bearing 5-membered ring.
Ernestine Nicaise Djuidje   +8 more
doaj   +1 more source

Unveiling the Potential of Metal and Non‐Metal Modified Porous Carbon for the Electrochemical Reduction of CO2

open access: yesCarbon Energy, EarlyView.
Earth‐abundant metal‐ and non‐metal‐modified porous carbons offer a highly tunable platform for electrochemical CO2 reduction. This review shows how electronic interactions, active‐site coordination, pore architecture, and cooperative catalytic effects jointly govern intermediate stabilization, product selectivity, and device‐relevant CO2RR performance.
Hussein A. Younus   +4 more
wiley   +1 more source

Polymer Molecular Interface Engineering—Enhanced Cu‐Based Catalysts for the CO2 Electroreduction Reaction

open access: yesCarbon Energy, EarlyView.
This review highlights polymer‐mediated interfacial engineering strategies for Cu‐based electrocatalysts toward enhanced CO2RR, including steering the electronic structure of Cu, enhancing CO2 adsorption and activation, regulating the reaction microenvironment, constructing a molecular protective layer, and stabilizing the key intermediate.
Haoquan Peng   +7 more
wiley   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

open access: yesChemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi   +6 more
wiley   +1 more source

Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases

open access: yesE-Journal of Chemistry, 2010
The ring system in which a benzene ring is fused to the 4,5-positions of imidazole is designated as benzimidazole. Condensations of 2-substituted benzimidazole derivatives were synthesized by different carboxylic acids using Mannich base and anti ...
B. Anil Reddy
doaj   +1 more source

A Naphthalene Monoimide Meisenheimer Complex as Strong Organic Hydride Donor for Metal‐Free CO2 Reduction

open access: yesChemistry – A European Journal, EarlyView.
A Meisenheimer complex derived from two‐fold reduction and protonation of naphthalene monoamide has been identified as a strong organic hydride donor which is able to reduce CO2. ABSTRACT Selective CO2 reduction to formate is challenging due to similar thermodynamics for the reaction to other products such as carbon monoxide and molecular hydrogen ...
C. Jasslie Nielsen   +5 more
wiley   +1 more source

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