Results 61 to 70 of about 636,119 (261)

ANTIBACTERIAL ACTIVITY OF BENZIMIDAZOLES 2-THIO, 2-AMINODERIVATIVES AND COMPLEXES OF BENZIMIDAZOLES WITH TRANSITIONAL METALS

Фармация и фармакология (Пятигорск), 2015
The literature data about antibacterial properties of benzimidazole 2-thio-, 2-aminoderivatives and benzimidazole complexes have been generalized and systematized in the review.
E. I. Mayboroda, V. N. Britsun
doaj   +1 more source

1H-benzimidazole derivatives as mammalian DNA topoisomerase I inhibitors [PDF]

, 2007
Benzimidazole is one of the most important heterocyclic groups manifesting various biological properties, such as antibacterial, antifungal, antimicrobial, antiprotozoal and antihelmintic activities.
Gunesi, H. Sernih, Gunes, H, Alpan, A. Selcen, Topcu, Zeki, Alpan, A   +4 more
core  

Facile Synthesis, Characterization and in vitro Antibacterial Efficacy of Functionalized 2-Substituted Benzimidazole Motifs

Indonesian Journal of Chemistry, 2019
A series of functionalized 2-substituted benzimidazole motifs was designed and successfully synthesized via thermal cyclization of 1,2-diaminobenzene on COOH end of L- leucine to achieve benzimidazole derivatives 6 as the essential precursor.
Olayinka Oyewale Ajani, Olaoluwasubomi Eneyeme Joseph, King Tamunodikibugerere Iyaye, Natasha October, Damilola Victoria Aderohunmu, Shade John Olorunshola, Oluwatosin Yemisi Audu   +6 more
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A review on biologically important benzimidazole derivatives

Results in Chemistry
Chemists have long been interested in the synthesis of benzimidazole derivatives, resulting in numerous studies on this heterocyclic compound. Its exceptional therapeutic efficacy in treating diseases has attracted further attention.
Vijayabharathi Sundharaj, V. Vijayakumar, S. Sarveswari   +2 more
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Synthesis and Analgesic Activity of Novel Derivatives of 1,2-Substituted Benzimidazoles

Journal of Chemistry, 2013
A series of novel 2-phenylhydrazinomethyl and 2-(2-hydroxyphenyl)-benzimidazole derivatives substituted at the N1-position of benzimidazole nucleus were synthesized as well as screened for analgesic activity.
Shobhit Srivastava, S. N. Pandeya, Meena K. Yadav, B. K. Singh   +3 more
doaj   +1 more source

Design and Synthesis of Benzimidazole-Chalcone Derivatives as Potential Anticancer Agents

Molecules, 2019
Numerous reports have shown that conjugated benzimidazole derivatives possess various kinds of biological activities, including anticancer properties.
Cheng-Ying Hsieh, Pi-Wen Ko, Yu-Jui Chang, Mohit Kapoor, Yu-Chuan Liang, Hsueh-Liang Chu, Hui-Hsien Lin, Jia-Cherng Horng, Ming-Hua Hsu   +8 more
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New Plant Growth Regulators of Benzimidazole Series

Chemistry Proceedings
Benzimidazole derivatives have a wide range of biological activity, including growth-regulating activity in relation to plants. The study of the structure-activity relationship (SAR) in a number of benzimidazole derivatives is important for the ...
Alena V. Yegorova, Anna E. Sklyar, Alevtina Yu. Yegorova, Vyacheslav S. Grinev   +3 more
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Synthesis, biological investigation, and docking studies of benzimidazole derivatives as butyrylcholinesterase and acetylcholinesterase inhibitors [PDF]

شیمی کاربردی روز
The cholinergic hypothesis is one of the hypotheses of Alzheimer's disease that shows the relationship between the onset and progression of the disease. One of the main ways to increase the level of acetylcholine is to inhibit cholinesterase enzymes. The
Maryam Rouhi, Sakineh Asghari, Zahra Ghanbari Masir   +2 more
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Design, synthesis, and evaluation of anxiolytic activity of 2-(4-phenylpiperazin-1-yl)-1H-benz[d]imidazole and 2-(4-phenylpiperazin-1-methyl)-1H-benz[d]imidazole derivatives

Future Journal of Pharmaceutical Sciences
Background In contemporary society, anxiety has become a widespread disorder leading to compromised well-being and heightened depressive states. Extensive literature reviews indicate the diverse biological effects of benzimidazole and piperazine ...
Bhavna Sunil Mahajan, Laxman A. Kawale, Vandana S. Nade, Supriya Unavane, Lida Sajimon, Prajakta Kapadnis   +5 more
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Preparation and mesomorphic properties of 1-methyl-1H-benzimidazole-based compounds

, 2018
A series of 1-methyl-1H-benzimidazole-based compounds, 2-(4ʹ-alkoxy-1,1ʹ-biphenyl-4-yl)-1-methyl- 1H-1,3-benzimidazole derivatives (nPPMx-M) with terminal hydrogen, methyl and nitro moieties (coded as nPPMH-M, nPPMM-M and nPPMN-M, respectively), were ...
Qiang Weng (810219), Pei Chen (252989), Yafei Hou (4559020), Xinbing Chen (810221), Aiai Gao (2610688), Zhongwei An (810222), Liyuan Ren (3862429), Longyan Duan (3862432)   +7 more
core   +1 more source