Results 201 to 210 of about 636,119 (261)

Synthesis and Biological Evaluation of Novel Amino and Amido Substituted Pentacyclic Benzimidazole Derivatives as Antiproliferative Agents. [PDF]

Int J Mol Sci
Perin N, Gulin M, Kos M, Persoons L, Daelemans D, Fabijanić I, Stojković MR, Hranjec M.   +7 more
europepmc   +1 more source

Inhibition of Shikimate Kinase from Methicillin-Resistant Staphylococcus aureus by Benzimidazole Derivatives. Kinetic, Computational, Toxicological, and Biological Activity Studies. [PDF]

Int J Mol Sci
Rios-Soto L, Hernández-Campos A, Tovar-Escobar D, Castillo R, Sierra-Campos E, Valdez-Solana M, Téllez-Valencia A, Avitia-Domínguez C.   +7 more
europepmc   +1 more source

Synthesis, Anticancer Activity, and In Silico Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer. [PDF]

ACS Omega
Abbade Y, Kisla MM, Hassan MA, Celik I, Dogan TS, Mutlu P, Ates-Alagoz Z.   +6 more
europepmc   +1 more source

Synthesis of ferrocenyl benzimidazole derivatives as novel anti-Toxoplasma gondii agents.

New J Chem
Ndlovu MT, Harding CR, Kaschula CH, Chellan P.   +3 more
europepmc   +1 more source

Arylamines QSAR-Based Design and Molecular Dynamics of New Phenylthiophene and Benzimidazole Derivatives with Affinity for the C111, Y268, and H73 Sites of SARS-CoV-2 PLpro Enzyme. [PDF]

Pharmaceuticals (Basel)
Sabadini G, Mellado M, Morales C, Mella J.   +3 more
europepmc   +1 more source

Benzimidazole Derivatives as Kinase Inhibitors

Current Medicinal Chemistry, 2014
Benzimidazole is a common kinase inhibitor scaffold and benzimidazole-based compounds interact with enzymes by multiple binding modes. In some cases, the benzimidazole acts as part of the hinge-binding motif, in others it has a scaffolding role without evidence for direct hinge binding. Several of these compounds are ATP-competitive inhibitors and show
GARUTI, LAURA, ROBERTI, MARINELLA, BOTTEGONI, GIOVANNI   +2 more
openaire   +5 more sources

Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine

Acta Pharmaceutica Sinica B, 2023
Cancer is the second leading cause of mortality globally which remains a continuing threat to human health today. Drug insensitivity and resistance are critical hurdles in cancer treatment; therefore, the development of new entities targeting malignant ...
Yeuan Ting Lee, Chern Ein Oon, Yi Jer Tan   +2 more
exaly   +3 more sources

Review- biological active benzimidazole derivatives

Results in Chemistry, 2021
In the field of Medicinal Chemistry, the uses of heterocyclic compounds increased day by day, because in many biological materials, heterocyclic compound is a part of its structure.
Balasaheb Pathare, Tanaji Bansode
exaly   +3 more sources

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Benzimidazole Derivatives

2021
GALLEY GUIDO, GROEBKE ZBINDEN KATRIN, HUNZIKER DANIEL, GUBA WOLFGANG, KRUMM DANNY, KRUMMENACHER DANIELA, HILBERT MANUEL   +6 more
  +9 more sources

A Panoramic Review of Benzimidazole Derivatives and their Potential Biological Activity

Mini-Reviews in Medicinal Chemistry, 2022
Socorro Leyva Ramos, Hiram Hernandez-Lopez   +1 more
exaly